Divisions of Pulmonary, Critical Care and Sleep Medicine, University of Florida Health Science Center, Gainesville, FL 32610-0225, USA.
Clin Transplant. 2010 Sep-Oct;24(5):610-4. doi: 10.1111/j.1399-0012.2009.01144.x.
We sought to investigate the role of autopsy diagnoses in lung transplantation by comparing the clinically derived cause of death with autopsy deduced cause of death in a cohort of lung transplant recipients. We retrospectively reviewed all consecutive autopsy findings on lung transplant recipients transplanted between March 1994 and March 2007. We reviewed medical records and our lung transplant database to determine the clinical diagnosis of cause of death based on the clinical assessment and discharge summary at the time of death. Our study showed that 21% of the autopsies performed on lung transplant recipients at our institution revealed findings unsuspected at the time of death. Myocardial infarction, pulmonary embolism, high grade acute cellular rejection and infections were the most frequently missed diagnoses. The autopsy remains a useful tool in confirming diagnostic accuracy in lung transplant recipients.
我们旨在通过比较临床死因和尸检推断死因，来研究尸检诊断在肺移植中的作用。我们回顾性分析了 1994 年 3 月至 2007 年 3 月期间所有连续接受肺移植的患者的尸检结果。我们查阅病历和肺移植数据库，以确定死亡时的临床评估和出院小结得出的临床死因诊断。我们的研究表明，我们机构对肺移植患者进行的尸检中，有 21%显示出在死亡时未被怀疑的发现。心肌梗死、肺栓塞、高级别急性细胞排斥反应和感染是最常被漏诊的疾病。尸检仍然是确认肺移植受者诊断准确性的有用工具。
