在资源有限的环境中，抗逆转录病毒疗法控制与艾滋病毒相关的结核病流行。

Antiretroviral therapy for control of the HIV-associated tuberculosis epidemic in resource-limited settings.

机构信息

The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa.

出版信息

Clin Chest Med. 2009 Dec;30(4):685-99, viii. doi: 10.1016/j.ccm.2009.08.010.

DOI:10.1016/j.ccm.2009.08.010

PMID:19925961

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2887494/

Abstract

Great progress has been made over the past few years in HIV testing in patients who have tuberculosis (TB) and in the scale-up of antiretroviral therapy. More than 3 million people in resource-limited settings were estimated to have started antiretroviral therapy by the end of 2007 and 2 million of these were in sub-Saharan Africa. However, little is known about what impact this massive public health intervention will have on the HIV-associated TB epidemic or how antiretroviral therapy might be used to best effect TB control. This article provides an in-depth review of these issues.

摘要

在过去几年中，在对患有结核病（TB）的患者进行 HIV 检测以及扩大抗逆转录病毒治疗方面取得了重大进展。据估计，到 2007 年底，资源有限的环境中有超过 300 万人开始接受抗逆转录病毒治疗，其中 200 万人在撒哈拉以南非洲。然而，对于这种大规模公共卫生干预对与 HIV 相关的结核病流行的影响，或者抗逆转录病毒治疗如何能够最好地用于结核病控制，人们知之甚少。本文深入探讨了这些问题。