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复杂眼眶重建的计算机辅助规划、立体光刻建模及术中导航:一项初步队列的描述性研究

Computer-assisted planning, stereolithographic modeling, and intraoperative navigation for complex orbital reconstruction: a descriptive study in a preliminary cohort.

作者信息

Bell R Bryan, Markiewicz Michael R

机构信息

Oral and Maxillofacial Surgery Service, Legacy Emanuel Hospital and Health Center, Oregon Health & Science University, Portland, OR, USA.

出版信息

J Oral Maxillofac Surg. 2009 Dec;67(12):2559-70. doi: 10.1016/j.joms.2009.07.098.

Abstract

PURPOSE

Post-traumatic or postablative enophthalmos and diplopia and/or facial asymmetry resulting from inaccurate restoration of orbital anatomy remain relatively frequent sequellae of complex orbital reconstruction. Recently, preoperative computer-assisted planning with virtual correction and construction of stereolithographic models have been combined with intraoperative navigation in an attempt to more accurately reconstruct the bony orbit and optimize treatment outcomes. The purpose of the present study is to review the authors' early experience with computer planning, stereolithographic modeling, and intraoperative navigation in a series of patients who underwent surgical treatment for a variety of complex post-traumatic and postablative orbital deformities.

PATIENTS AND METHODS

The investigators initiated a retrospective chart review, and a sample of patients was derived from the population of patients at Legacy Emanuel Hospital, Portland, OR, between 2007 and 2008. Each patient's anatomy was assessed in multiplanar (axial, coronal, sagittal) and 3-dimensional computed tomography (CT) hard-tissue views; virtual correction was made using the uninjured or anatomically correct side by creating a mirror image that was superimposed on the traumatized side. The internal orbit was reconstructed with the previously contoured titanium mesh. The external orbital frame was reduced or repositioned and stabilized using 1.3-mm and/or 1.5-mm titanium plates and screws. The patient's position was identified with a digital reference frame that was fixed to an adhesive mask. Intraoperative navigation was then used to assess the accuracy of the restored internal and external orbital anatomy by assessing various points on the virtual image at the workstation. All patients received a postoperative CT scan, and the preoperative and postoperative images were compared and subjectively analyzed. To be included in the sample, patients must have undergone reconstruction for complex primary or secondary unilateral orbital deformities secondary to traumatic injury or ablative procedure using computer-assisted treatment during the study enrollment period. Criteria for using computer-assisted navigation were unilateral, clinically significant disruption of the internal and/or external orbit, that involved more than one orbital wall and that resulted in or had the potential to result in enophthalmos, diplopia, ocular dysmotility, or facial asymmetry. Patients excluded from the review were those who underwent orbital reconstructing using traditional (non-computer-assisted) techniques. Demographic, etiological, treatment, and outcome variables were recorded and analyzed. Outcome measures included globe position, ocular motility, facial symmetry, and complications. Poor outcome was defined as clinically perceptible enophthalmos, persistent dipolopia, facial asymmetry/malar flattening, or ocular dysmotility.

RESULTS

Fifteen consecutive patients with complex primary or secondary unilateral post-traumatic and postablative orbital deformities received computer-assisted treatment. Anatomic restoration of internal and external orbital contours was obtained in all but 1 patient based on a comparison of preoperative and postoperative CT scans. Further evaluation of the postoperative CT images compared favorably to the virtually planned reconstructions. Despite favorable restoration of internal and external bony anatomy, the soft-tissue limitations were not completely overcome in some patients with secondary deformities. Suboptimal correction of globe projection occurred in three patients undergoing secondary enophthalmos repair because of severe, intraconal, soft-tissue scarring posterior to the equator of the globe. Complications occurred in 4 patients.

CONCLUSIONS

Preoperative computer modeling and intraoperative navigation provides a useful guide for and presumably more accurate reconstruction of complex orbital injuries and postablative orbital defects. Although probably not necessary for routine use in small orbital blowout fractures, its use in a shattered orbit or high-velocity injury resulting in severe disruption of the internal and external orbit shows promise.

摘要

目的

因眼眶解剖结构恢复不准确导致的创伤后或切除术后眼球内陷、复视和/或面部不对称,仍然是复杂眼眶重建相对常见的后遗症。最近,术前计算机辅助规划结合虚拟矫正和实体模型构建,并与术中导航相结合,试图更准确地重建眼眶骨骼并优化治疗效果。本研究的目的是回顾作者在一系列因各种复杂创伤后和切除术后眼眶畸形接受手术治疗的患者中,使用计算机规划、实体模型构建和术中导航的早期经验。

患者与方法

研究人员开展了一项回顾性病历审查,样本取自2007年至2008年俄勒冈州波特兰市伊曼纽尔遗产医院的患者群体。在多平面(轴位、冠状位、矢状位)和三维计算机断层扫描(CT)硬组织视图中评估每位患者的解剖结构;通过创建一个镜像并将其叠加在受伤侧,使用未受伤或解剖结构正确的一侧进行虚拟矫正。用预先塑形的钛网重建眼眶内部。使用1.3毫米和/或1.5毫米钛板及螺钉对眼眶外框架进行复位或重新定位并固定。通过固定在粘贴式面罩上的数字参考框架确定患者的位置。然后使用术中导航,通过在工作站评估虚拟图像上的各个点,来评估眼眶内部和外部解剖结构恢复的准确性。所有患者均接受术后CT扫描,并对术前和术后图像进行比较和主观分析。要纳入样本,患者必须在研究入组期间因创伤性损伤或切除手术导致的复杂原发性或继发性单侧眼眶畸形,接受了计算机辅助治疗。使用计算机辅助导航的标准为单侧、眼眶内部和/或外部临床上明显的破坏,累及一个以上眼眶壁,并导致或有可能导致眼球内陷、复视、眼球运动障碍或面部不对称。被排除在审查之外的患者是那些使用传统(非计算机辅助)技术进行眼眶重建的患者。记录并分析人口统计学、病因、治疗和结果变量。结果指标包括眼球位置、眼球运动、面部对称性和并发症。不良结果定义为临床上可察觉到的眼球内陷、持续性复视、面部不对称/颧骨扁平或眼球运动障碍。

结果

15例连续的因复杂原发性或继发性单侧创伤后和切除术后眼眶畸形患者接受了计算机辅助治疗。根据术前和术后CT扫描比较,除1例患者外,所有患者眼眶内部和外部轮廓均获得了解剖学上的恢复。术后CT图像的进一步评估与虚拟规划的重建结果相比良好。尽管眼眶内部和外部骨骼解剖结构恢复良好,但一些继发性畸形患者的软组织限制并未完全克服。3例接受继发性眼球内陷修复的患者,由于眼球赤道后方严重的圆锥内软组织瘢痕形成,眼球突出矫正欠佳。4例患者出现并发症。

结论

术前计算机建模和术中导航为复杂眼眶损伤和切除术后眼眶缺损的重建提供了有用的指导,且可能更准确。虽然对于小的眼眶爆裂性骨折常规使用可能不必要,但其在粉碎性眼眶或导致眼眶内部和外部严重破坏的高速损伤中的应用显示出前景。

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