Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Clin Nutr. 2010 Aug;29(4):477-81. doi: 10.1016/j.clnu.2009.10.009. Epub 2009 Nov 18.
BACKGROUND & AIMS: This study was undertaken to describe anthropometry, body composition parameters and assess serum levels of leptin and other biochemical markers of the nutritional status in a sample of Egyptian children with cerebral palsy(CP).
Anthropometric measurements (body weight, knee height, head, mid-upper arm, waist and hip circumferences, triceps and subscapular skin-fold thickness) were taken. Using the bioelectrical impedance technique, total body water(TBW), fat-free mass, fat mass, fat percentage and basal metabolic rate(BMR) were calculated. Serum levels of total proteins, albumin, ferritin and leptin were measured. Results were compared to that of healthy controls.
Patients had significantly lower anthropometric measurements than controls, except for mid-upper arm and hip circumferences, and subscapular skin-fold thickness which were not different in both groups. Fat mass, fat free mass, fat percentage, TBW and BMR were lower in the patients. Serum protein and leptin levels were not different in patients and controls, though other biochemical markers were reduced in the patients. Patients with more severe motor handicap had lower skin-fold thickness, fat percentage and serum ferritin than those with milder affection.
Parameters of growth, body composition analysis and nutritional status are significantly altered in CP patients especially those with severe motor handicap and oromotor dysfunction.
本研究旨在描述埃及脑瘫儿童的人体测量学、身体成分参数,并评估瘦素和其他营养状况生化标志物的血清水平。
进行了人体测量学测量(体重、膝高、头围、中上臂围、腰围和臀围、肱三头肌和肩胛下角皮褶厚度)。使用生物电阻抗技术,计算了总体水(TBW)、去脂体重、脂肪量、体脂百分比和基础代谢率(BMR)。测量了血清总蛋白、白蛋白、铁蛋白和瘦素水平。将结果与健康对照组进行比较。
患者的人体测量学测量值明显低于对照组,除中上臂围和臀围以及肩胛下角皮褶厚度在两组之间无差异外。患者的脂肪量、去脂体重、体脂百分比、TBW 和 BMR 较低。患者的血清蛋白和瘦素水平与对照组无差异,但患者的其他生化标志物水平降低。运动功能障碍较重的患者的皮褶厚度、体脂百分比和血清铁蛋白低于运动功能障碍较轻的患者。
脑瘫患者的生长、身体成分分析和营养状况参数明显改变,尤其是运动功能障碍较重和口运动功能障碍的患者。