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精神分裂症患者和照护者心理教育的性别差异。

Gender differences in patient and caregiver psychoeducation for schizophrenia.

机构信息

Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar der Technischen, Universität München, Möhlstrasse, 26, 81675 München, Germany.

出版信息

Eur Psychiatry. 2010 Jan;25(1):39-46. doi: 10.1016/j.eurpsy.2009.08.001. Epub 2009 Nov 18.

Abstract

OBJECTIVE

The aim of this research is to detect gender-related differences in patients and caregivers regarding knowledge about schizophrenia and attitudes towards drugs as well as gender as predictor for changes in these variables during psychoeducation.

METHODS

Data sets of one randomised-controlled (study 1) and one naturalistic psychoeducation study (study 2) were reanalysed. Main outcome measures (knowledge about schizophrenia, drug attitude, confidence in medication) were assessed at baseline, post-intervention and 12 months after index discharge.

RESULTS

The reanalysed samples consisted in total of 1002 patients and 176 caregivers. In study 2, baseline knowledge was significantly better in male patients and female caregivers. All participants improved significantly their knowledge. The amount of knowledge gain did not differ between genders in either study or either group. Gender was not a major predictor of baseline knowledge or knowledge gain. Only in study 1 did gender significantly impact the knowledge gain from baseline to follow-up. Regarding improvement of drug attitude, females seemed to benefit significantly better from psychoeducation. In both studies, however, changes in drug attitudes respectively confidence in medication were best explained by lower corresponding baseline scores, not gender. Patients' gender did not influence outcomes of their caregivers.

CONCLUSION

Our findings suggest that psychoeducational programs might be better adapted to males in order to improve their drug attitude. Concerning knowledge, gender-related changes do not seem to be necessary.

摘要

目的

本研究旨在检测精神分裂症患者和照料者在知识、药物态度方面的性别差异,以及性别作为预测因素在心理教育过程中这些变量变化的情况。

方法

重新分析了一项随机对照研究(研究 1)和一项自然主义心理教育研究(研究 2)的数据。主要结局指标(精神分裂症知识、药物态度、对药物的信心)在基线、干预后和索引出院后 12 个月进行评估。

结果

重新分析的样本共包括 1002 名患者和 176 名照料者。在研究 2 中,男性患者和女性照料者的基线知识明显更好。所有参与者的知识均显著提高。在两项研究或任何一组中,性别都不是知识增益的主要预测因素。性别仅在研究 1 中从基线到随访的知识增益方面具有显著影响。在药物态度方面,女性似乎从心理教育中获益更大。然而,在两项研究中,药物态度和对药物的信心的变化都可以通过较低的基线分数来更好地解释,而不是性别。患者的性别并不影响其照料者的结局。

结论

我们的研究结果表明,心理教育计划可能需要更好地适应男性,以改善他们的药物态度。关于知识,性别相关的变化似乎并不是必要的。

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