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身体适应性预测唐氏综合征患者的功能任务。

Physical fitness predicts functional tasks in individuals with Down syndrome.

机构信息

Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USA.

出版信息

Med Sci Sports Exerc. 2010 Feb;42(2):388-93. doi: 10.1249/MSS.0b013e3181b07e7a.

DOI:10.1249/MSS.0b013e3181b07e7a
PMID:19927019
Abstract

UNLABELLED

Individuals with Down syndrome (DS) exhibit reduced strength and aerobic capacity, which may limit their ability to perform functional tasks of daily living.

PURPOSE

This study was conducted to examine the relationship between timed performance on functional tasks of daily living and age, knee isometric strength, and peak aerobic capacity in a group of individuals with DS.

METHODS

This was a cross-sectional study involving 35 individuals (27 +/- 7.5 yr) with DS. Participants completed an isometric test of knee extensor and flexor strength, an individualized exercise test to measure peak aerobic capacity, and three timed functional tasks of daily living, which included chair rise, gait speed, and stair ascent and descent. Multiple regression analyses were performed to examine the relationship between timed task performance and age, knee isometric strength, and peak aerobic capacity.

RESULTS

The multiple regression models explained 11-29% of the variance in timed task performance. Knee extensor strength was the most influential variable in predicting timed task performance (squared semipartial correlation coefficient [sr2] = 0.11-0.20), followed by aerobic capacity (sr2 = 0.10-0.14). Age was not a significant predictor of timed task performance.

CONCLUSION

These findings suggest that physical fitness (defined here as aerobic capacity and knee extensor strength) limits the ability of adults with DS to perform functional tasks of daily living. Randomized controlled trials should be performed to test the probable causal relationship between exercises designed to improve physical fitness and functional tasks of daily living.

摘要

未加标签

唐氏综合征(DS)患者的力量和有氧能力均有所下降,这可能限制了他们完成日常功能任务的能力。

目的

本研究旨在检验日常生活功能任务的计时表现与年龄、膝关节等长肌力和峰值有氧能力之间的关系。

方法

本研究为一项涉及 35 名 DS 患者(27 ± 7.5 岁)的横断面研究。参与者完成了膝关节伸肌和屈肌等长肌力测试、个性化的峰值有氧能力测试和 3 项日常生活功能任务的计时测试,包括椅子起身、步行速度和上下楼梯。进行多元回归分析以检验计时任务表现与年龄、膝关节等长肌力和峰值有氧能力之间的关系。

结果

多元回归模型解释了 11-29%的计时任务表现的方差。膝关节伸肌力量是预测计时任务表现的最具影响力的变量(平方偏部分相关系数 [sr2] = 0.11-0.20),其次是有氧能力(sr2 = 0.10-0.14)。年龄不是计时任务表现的显著预测因素。

结论

这些发现表明,身体健康(在此定义为有氧能力和膝关节伸肌力量)限制了 DS 成年患者完成日常功能任务的能力。应进行随机对照试验,以检验旨在提高身体健康的运动与日常功能任务之间的可能因果关系。

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