Fraunhofer Institut Verfahrenstechnik und Verpackung, Giggenhauserstr. 35, D-85354 Freising, Germany.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2009 Dec;26(12):1581-91. doi: 10.1080/02652030903174831.
Most food packages and food-contact materials are manufactured using adhesives. The European Union regulates all food-contact materials, as their constituents may not contaminate food and endanger consumers' health. In contrast to plastics which are regulated by positive lists of authorized ingredients, adhesives have not yet a specific regulation. The MIGRESIVES project aimed to elaborate a scientific global risk-assessment approach to meet current general European Union regulatory requirements and as a basis for future specific European Union legislation as well as to provide the industry, especially small and medium-sized enterprises, a tool to ensure that migration from adhesives is in compliance with the regulatory requirements. The idea was to demonstrate that consumers' exposure to chemicals released by adhesives is in many cases below levels of concern. Technical/scientific knowledge from industry and research institutes will be merged into a collective research endeavour gathering all stakeholders. The major milestones are (1) the classification of adhesives according to chemistry and uses, (2) the test strategies based on physico-chemical behaviour of adhesives, (3) modelling migration/exposure from adhesives, (4) providing guidelines to integrate the risk-assessment approach into the daily life of companies, (5) the feasibility of applying the toxicological approach from the European Union BIOSAFEPAPER project, and (6) extensive training/education to small and medium-sized enterprises (SMEs) and large dissemination for general adoption of the concept in Europe.
大多数食品包装和食品接触材料都是使用粘合剂制造的。欧盟对所有食品接触材料进行监管,因为其成分不得污染食品并危害消费者健康。与受授权成分正面清单监管的塑料不同,粘合剂尚未有具体的规定。MIGRESIVES 项目旨在制定一种科学的全球风险评估方法,以满足当前欧盟的一般监管要求,并作为未来欧盟特定立法的基础,并为行业,特别是中小企业提供一种工具,以确保粘合剂的迁移符合监管要求。其理念是证明消费者接触到的粘合剂释放出的化学物质在许多情况下低于关注水平。来自行业和研究机构的技术/科学知识将合并到一个汇集所有利益攸关方的集体研究工作中。主要里程碑包括:(1) 根据化学和用途对粘合剂进行分类;(2) 基于粘合剂物理化学行为的测试策略;(3) 对来自粘合剂的迁移/暴露进行建模;(4) 提供将风险评估方法纳入公司日常运作的指南;(5) 应用欧盟 BIOSAFEPAPER 项目毒理学方法的可行性;(6) 对中小企业(SME)进行广泛的培训/教育,并在欧洲广泛传播,以普遍采用这一概念。