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美国甲状腺癌发病率的地理差异以及新泽西州、纽约州和宾夕法尼亚州核反应堆附近的聚集情况。

Geographic variation in U.S. thyroid cancer incidence and a cluster near nuclear reactors in New Jersey, New York, and Pennsylvania.

作者信息

Mangano Joseph J

机构信息

Radiation and Public Health Project, Ocean City, NJ 08226, USA.

出版信息

Int J Health Serv. 2009;39(4):643-61. doi: 10.2190/HS.39.4.c.

DOI:10.2190/HS.39.4.c
PMID:19927407
Abstract

In the United States, thyroid cancer incidence (along with liver cancer) is increasing more rapidly than any other malignancy, rising nearly threefold from 1980 to 2006. Improved diagnosis has been proposed by some as the major reason for this change, while others contend that additional factors also account for the increase. Among U.S. states, 2001-2005 age-adjusted thyroid cancer incidence rates vary from 5.4 to 12.8 per 100,000. County-specific incidence data, available for the first time, document that most U.S. counties with the highest thyroid cancer incidence are in a contiguous area of eastern Pennsylvania, New Jersey, and southern New York State. Exposures to radioactive iodine emissions from 16 nuclear power reactors within a 90-mile radius in this area indicate that these emissions are a likely etiological factor in rising thyroid cancer incidence rates.

摘要

在美国,甲状腺癌发病率(与肝癌一样)的增长速度比其他任何恶性肿瘤都要快,从1980年到2006年几乎增长了两倍。一些人认为诊断技术的改进是这一变化的主要原因,而另一些人则认为还有其他因素导致了发病率的上升。在美国各州中,2001 - 2005年年龄调整后的甲状腺癌发病率从每10万人5.4例到12.8例不等。首次获得的特定县发病率数据表明,美国甲状腺癌发病率最高的大多数县都集中在宾夕法尼亚州东部、新泽西州和纽约州南部的相邻地区。该地区半径90英里范围内16座核反应堆排放的放射性碘表明,这些排放可能是甲状腺癌发病率上升的一个病因。

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