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标准奇偶数范式与遗漏范式的P300比较:对外源/内源贡献的启示

Comparisons of P300s from standard oddball and omitted paradigms: implications to exogenous/endogenous contributions.

作者信息

McCullagh Jennifer, Weihing Jeffrey, Musiek Frank

机构信息

University of Connecticut, 850 Bolton Rd U-1085, Storrs, CT 06269, USA.

出版信息

J Am Acad Audiol. 2009 Mar;20(3):187-95; quiz 219. doi: 10.3766/jaaa.20.3.5.

DOI:10.3766/jaaa.20.3.5
PMID:19927689
Abstract

PURPOSE

To compare the amplitude, latency, morphology, and threshold of the auditory P300 using standard oddball and omitted paradigms.

RESEARCH DESIGN

P300 waveforms were measured from the Cz electrode site. Frequent stimuli for both paradigms were 1000 Hz tone bursts. Target stimuli for the standard oddball paradigm were 2000 Hz tone bursts and an omitted stimulus, or silent gap, for the omitted paradigm.

STUDY SAMPLE

Fifteen bilaterally normal-hearing young adults.

RESULTS

There were significantly lower amplitudes, poorer morphology, and higher thresholds for the P300 using an omitted paradigm compared to the standard oddball paradigm.

CONCLUSION

These results suggest that the auditory P300 could have a larger exogenous component than traditionally thought.

摘要

目的

使用标准的奇偶数范式和遗漏范式比较听觉P300的波幅、潜伏期、形态和阈值。

研究设计

从Cz电极部位测量P300波形。两种范式的频繁刺激均为1000Hz的短纯音。标准奇偶数范式的目标刺激为2000Hz的短纯音,遗漏范式的目标刺激为遗漏刺激或静音间隙。

研究样本

15名双侧听力正常的年轻成年人。

结果

与标准奇偶数范式相比,使用遗漏范式时P300的波幅显著更低、形态更差且阈值更高。

结论

这些结果表明,听觉P300可能具有比传统认知中更大的外源性成分。

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