Demetriades Neophytos, Hanford Hope, Laskarides Constantinos
Department of Oral and Maxillofacial Surgery, Tufts University School of Dental Medicine , USA.
J Mass Dent Soc. 2009 Fall;58(3):24-7.
This article reviews the oral manifestations of Behçet's Syndrome that have been discussed in the literature and presents the success of the use of CO2-laser for recurrent aphthous stomatitis (RAS). Behçet's Syndrome is a multisystem inflammatory disease that has the capacity to affect nearly every human system. It is characterized by a wide range of clinical features. In particular the defining symptom in most cases is recurrent aphthous stomatitis present in the oral cavity. RAS is the most common inflammatory ulcerative condition to affect the oral cavity and is characterized by localized, painful ulcers that may be a manifestation of more complicated diseases, such as Behçet's Syndrome. There is no effective treatment for RAS. In most cases, RAS is managed by anesthetic topical treatments, topical or systemic steroids, or antibiotics. More recently, though, there has been evidence of possible benefit from treatment of aphthous lesions with CO2-lasers. Our experience treating a patient who suffered from Behçet's Syndrome and RAS showed transient pain relief with the use of CO2 ablative laser as a monotherapy.
本文回顾了文献中讨论的白塞氏综合征的口腔表现，并介绍了使用二氧化碳激光治疗复发性阿弗他口炎（RAS）的成功案例。白塞氏综合征是一种多系统炎症性疾病，几乎能够影响人体的每个系统。它具有广泛的临床特征。特别是在大多数情况下，其标志性症状是口腔中出现复发性阿弗他口炎。RAS是影响口腔最常见的炎症性溃疡性疾病，其特征是局部疼痛性溃疡，可能是更复杂疾病（如白塞氏综合征）的一种表现。目前尚无针对RAS的有效治疗方法。在大多数情况下，RAS通过局部麻醉治疗、局部或全身使用类固醇或抗生素来处理。不过，最近有证据表明，用二氧化碳激光治疗阿弗他病变可能有益。我们治疗一名患有白塞氏综合征和RAS患者的经验表明，使用二氧化碳消融激光作为单一疗法可使疼痛得到短暂缓解。
