白塞病和阿弗他溃疡患者的急性期蛋白与补体C9
Acute phase proteins and C9 in patients with Behcet's syndrome and aphthous ulcers.
作者信息
Adinolfi M, Lehner T
出版信息
Clin Exp Immunol. 1976 Jul;25(1):36-9.
Abstract
Estimation of the concentration of C9, C-reactive protein (CRP) and alpha1-antitrypsin in forty sera from patients with Behcet's syndrome and recurrent oral ulcers showed significantly increased amounts of C9 and CRP in Behcet's syndrome. The concentration of C9 was also significantly raised in recurrent oral ulceration, though to a lesser extent than in Behcet's syndrome. The assay C9 and CRP might be useful in the differential diagnosis of Behcet's syndrome, especially from recurrent oral ulcers. It is suggested that during epithelial inflammation in recurrent oral ulcers some of the acute phase proteins are increased and in some patients these may modulate the immunological mechanism in such a way as to induce a transition from focal oral ulceration to the multifocal Behcet's syndrome.
摘要
对40例白塞病患者和复发性口腔溃疡患者血清中C9、C反应蛋白（CRP）和α1-抗胰蛋白酶浓度的测定显示，白塞病患者血清中C9和CRP含量显著升高。复发性口腔溃疡患者的C9浓度也显著升高，但其升高程度低于白塞病患者。检测C9和CRP可能有助于白塞病的鉴别诊断，尤其是与复发性口腔溃疡的鉴别。提示在复发性口腔溃疡的上皮炎症过程中，一些急性期蛋白会增加，在某些患者中这些蛋白可能以某种方式调节免疫机制从而诱导从局灶性口腔溃疡转变为多灶性白塞病。
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