Weber H, Ruprecht L, Enders S
Division of Cardiology, Hospital Bogenhausen, Munich, West Germany.
Angiology. 1991 Jan;42(1):15-22. doi: 10.1177/000331979104200103.
A model for testing transluminal recanalization techniques was developed. Fragments of human atherosclerotic coronary arteries were transplanted into carotid arteries of dogs and evaluated by angiographic, angioscopic, and histologic study within a three-month period. An inflammatory response was most intense within the first week. By two weeks no inflammation was noted. Total occlusion (n = 13) and stenosis (n = 11) of the carotid arteries were achieved without complications. The model is easy to produce within a short period and the arterial occlusion resembles human vascular disease. This model has been used to evaluate laser recanalization of vascular obstructions.
开发了一种用于测试腔内再通技术的模型。将人类动脉粥样硬化冠状动脉碎片移植到狗的颈动脉中，并在三个月内通过血管造影、血管内镜和组织学研究进行评估。炎症反应在第一周最为强烈。到两周时未观察到炎症。实现了颈动脉的完全闭塞（n = 13）和狭窄（n = 11），且无并发症。该模型易于在短时间内建立，动脉闭塞类似于人类血管疾病。此模型已用于评估血管阻塞的激光再通。
