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[评估门诊心脏康复对缺血性心脏病患者勃起功能障碍严重程度的影响]

[Evaluation of ambulatory cardiac rehabilitation influence on the intensity of erectile dysfunction in patients with ischemic heart disease].

作者信息

Kałka Dariusz, Sobieszczańska Małgorzata, Pilecki Witold, Szawrowicz-Pełka Teresa, Marciniak Wojciech, Sebzda Tadeusz, Turbański Jacek, Palczewska Violetta, Adamus Jerzy

机构信息

Akademia Medyczna we Wrocławiu, Katedra Patofizjologii, Zakład Elektrokardiologii i Prewencji Chorób Sercowo-Naczyniowych.

出版信息

Pol Merkur Lekarski. 2009 Oct;27(160):290-5.

Abstract

UNLABELLED

Considering a progressive course of cardiovascular disease, often leading to premature death, and difficulty in obtaining long-lasting stabilization of clinic state, it is deeply justified to take preventive interventions completing repairing actions and pharmacotherapy. Addressing various preventive programs to the patients with CVD, we put a special emphasis to simple and low-cost modification of physical activity, which has a beneficial influence on the circulatory system. As it has been proved, protective action of physical activity on the vessels concerns the whole arterial system including the vessels responsible for erectile dysfunction (ED) creation.

THE AIM OF THE STUDY

The analysis of the influence of physical activity modification, taking place within frames of a six-month supervised cardiac rehabilitation, on ED intensification in the population with ischemic heart disease (IHD).

MATERIAL AND METHODS

The analysis has been conducted on 129 patients with IHD, whose preliminary test IIEF-5 (International Index of Erectile Function-5) showed < or =21 scores, which justified ED diagnosis. The analyzed group consisted of 98 patients with IHD at the mean age of 62.35 +/- 8.88 years, who were subjected to the six-month cardiologic rehabilitation. The testing group comprises 31 patients with IHD at the mean age of 61.71 +/- 7.35, who were not rehabilitated for objective reasons. The patients of both groups filled in an IIEF-5 questionnaire twice, at the interval of six months.

RESULTS

As a result of cardiologic rehabilitation in the analyzed group, a statistically significant increase in scores occurred in the IIEF5 test, from 11.88 +/- 6.2 to 13.69 +/- 7.07, which was not observed in the control group. Moreover, a division of the analyzed group into ED intensity categories (severe, medium-severe, moderate, light) confirmed the occurrence of significant changes of ED intensity for subsequent ED severity categories. For the subsequent ED intensity categories, from the greatest to the lightest, the statistically significant increase of the scores from a sheet IIEF-5: 4.66 +/- 0.98 vs. 5.34 +/- 1.41 (p < 0.01); 9.5 +/- 1.2 vs. 10.9 +/- 1.58 (p < 0.01); 14.67 +/- 1.22 vs. 17.7 +/- 1.80 (p < 0.01) and 19.62 +/- 1.11 vs. 21.85 +/- 1.23 (p < 0.01) has been found. Bearing in mind the dependence of results on the credibility of data from the sheet IIEF-5, the last element was the analysis of 'truthfulness test', which has not shown any statistically significant differences obtained for first and next filling in the questionnaire.

CONCLUSIONS

The performed analyses allowed drawing the conclusions. A six-month cardiac rehabilitation cycle led to a significant positive modification of erectile dysfunction intensity. The greatest positive ED modification occurred at the groups of the patients, in whom the erectile dysfunction intensity was the smallest.

摘要

未标注

考虑到心血管疾病呈进行性发展,常导致过早死亡,且难以实现临床状态的长期稳定,采取预防性干预措施以补充修复行动和药物治疗是完全合理的。针对心血管疾病患者开展各种预防项目时,我们特别强调对体育活动进行简单且低成本的调整,这对循环系统具有有益影响。事实证明,体育活动对血管的保护作用涉及整个动脉系统,包括与勃起功能障碍(ED)形成有关的血管。

研究目的

分析在为期六个月的有监督心脏康复框架内进行的体育活动调整对缺血性心脏病(IHD)患者勃起功能障碍加重情况的影响。

材料与方法

对129例IHD患者进行了分析,其初步的国际勃起功能指数-5(IIEF-5)测试得分≤21分,这证明了ED的诊断。分析组由98例IHD患者组成,平均年龄为62.35±8.88岁,他们接受了为期六个月的心脏康复治疗。测试组包括31例IHD患者,平均年龄为61.71±7.35岁,由于客观原因未接受康复治疗。两组患者均在六个月的间隔内两次填写IIEF-5问卷。

结果

分析组经过心脏康复治疗后,IIEF5测试得分有统计学意义的显著增加,从11.88±6.2增加到13.69±7.07,而对照组未观察到这种情况。此外,将分析组按ED强度类别(重度、中重度、中度、轻度)划分,证实了后续ED严重程度类别中ED强度发生了显著变化。对于后续的ED强度类别,从最重到最轻,IIEF-5量表得分有统计学意义的显著增加:4.66±0.98对5.34±1.41(p<0.01);9.5±1.2对10.9±1.58(p<0.01);14.67±1.22对17.7±1.80(p<0.01);19.62±1.11对21.85±1.23(p<0.01)。考虑到结果对IIEF-5量表数据可信度的依赖性,最后一项是“真实性测试”分析,该分析未显示首次和下次填写问卷所获得的任何统计学显著差异。

结论

所进行的分析得出了结论。为期六个月的心脏康复周期导致勃起功能障碍强度有显著的正向改善。勃起功能障碍强度最小的患者组中,ED改善最为明显。

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