From Vision Institute, Federal University of São Paulo, Department of Ophthalmology, São Paulo, Brazil.
J Refract Surg. 2010 Aug;26(8):600-4. doi: 10.3928/1081597X-20091105-03.
To assess the change in corneal volume and laser ablation volume over time after LASIK using a rotating Scheimpflug camera.
Twenty-six patients (49 eyes) underwent LASIK. Pentacam Scheimpflug measurements were performed pre- and postoperatively at 1, 3, 7, 15, and 30 days. Central corneal thickness, total corneal volume (10-mm diameter), and partial corneal volumes (3, 5, and 7 mm) based on the apex of the cornea, were measured. Main outcome measures were differences between pre- and postoperative volume measurements of total and partial corneal regions, volume changes over time postoperatively, and comparison between laser ablation volume and corneal volume.
A strong linear relationship was noted between spherical equivalent refraction and laser ablation volume (r = -0.931, P < .0001). Furthermore, 30 days after LASIK, a strong linear relationship was noted between planned thickness and achieved thickness (r = 0.9457, P < .001). Corneal volumes for 3-, 5-, and 7-mm diameter regions significantly decreased over time postoperatively (one-way analysis of variance, P < .05).
Alterations in corneal volume correlated with laser ablation volume when the diameter of the region considered was 3, 5, or 7 mm from the corneal apex.
使用旋转式 Scheimpflug 相机评估 LASIK 术后角膜体积和激光消融体积随时间的变化。
26 名患者（49 只眼）接受了 LASIK 手术。在术前和术后 1、3、7、15 和 30 天使用 Pentacam Scheimpflug 进行测量。测量中央角膜厚度、基于角膜顶点的全角膜体积（10mm 直径）和部分角膜体积（3、5 和 7mm）。
全角膜和部分角膜区域的术前和术后体积测量值之间的差异、术后随时间的体积变化以及激光消融体积与角膜体积之间的比较。
球镜等效折射与激光消融体积之间存在很强的线性关系（r = -0.931，P <.0001）。此外，在 LASIK 术后 30 天，计划厚度与实际厚度之间存在很强的线性关系（r = 0.9457，P <.001）。从角膜顶点开始的 3、5 和 7mm 直径区域的角膜体积随术后时间明显减少（单因素方差分析，P <.05）。
当考虑的区域直径为角膜顶点的 3、5 或 7mm 时，角膜体积的变化与激光消融体积相关。
