Department of Ophthalmology, Ophthalmic Research Center, Shaheed Beheshti Medical University, Tehran, Iran.
J Cataract Refract Surg. 2010 Sep;36(9):1543-9. doi: 10.1016/j.jcrs.2010.03.042.
To compare central corneal thickness (CCT) measurements obtained with a dual Scheimpflug camera system (Galilei), a scanning-slit topographer (Orbscan II), and an ultrasound (US) pachymeter (SP-2000) after photorefractive keratectomy (PRK) for myopia.
Ophthalmic Research Center, Labbafinejad Medical Center, Tehran, Iran.
This prospective study enrolled patients who had PRK to correct myopia or myopic astigmatism and a postoperative follow-up of at least 5 months. The CCT was measured in a single session using Scheimpflug imaging, scanning-slit topography, and US pachymetry. Data were analyzed with paired t tests, linear regression, and Bland-Altman plots.
The mean CCT in the 100 eyes (50 patients) was 524.06 microm +/- 38.56 (SD) with Scheimpflug imaging, 505.92 +/- 47.35 microm with scanning-slit topography, and 496.97 +/- 42.74 microm with US pachymetry. The lower to upper 95% limits of agreement (LoA) with US pachymetry were 2.4 to 51.8 microm for Scheimpflug imaging and -22.2 to 40.1 microm for scanning-slit topography. After application of a correction factor (0.95), the mean corrected Scheimpflug CCT measurement was 497.33 +/- 36.59 microm and the lower to upper 95% LoA with US pachymetry were -25.9 to 25.5 microm. The acoustic factor for scanning-slit topography was 0.94.
The CCT measurements in eyes that had PRK were thicker with Scheimpflug imaging than with US pachymetry or scanning-slit topography in the late postoperative period. With application of a correction factor, the Scheimpflug measurements were closer to US pachymetry values and had better agreement than scanning-slit topography.
比较准分子激光屈光性角膜切削术（PRK）治疗近视后，应用双重Scheimpflug 相机系统（Galilei）、扫描 slit topography（Orbscan II）和超声角膜测厚仪（SP-2000）测量中央角膜厚度（CCT）的结果。
伊朗德黑兰 Labbafinejad 医疗中心眼科研究中心。
本前瞻性研究纳入了接受 PRK 治疗近视或近视散光且术后随访至少 5 个月的患者。单次应用 Scheimpflug 成像、扫描 slit topography 和超声角膜测厚仪测量 CCT。数据采用配对 t 检验、线性回归和 Bland-Altman 图进行分析。
100 只眼（50 例患者）的平均 CCT 分别为 Scheimpflug 成像 524.06 µm±38.56（SD）、扫描 slit topography 505.92 µm±47.35 µm和超声角膜测厚仪 496.97 µm±42.74 µm。与超声角膜测厚仪相比，Scheimpflug 成像的下、上限 95%一致性界限（LoA）为 2.451.8 µm，扫描 slit topography 为-22.240.1 µm。应用校正因子（0.95）后，Scheimpflug 校正 CCT 平均测量值为 497.33 µm±36.59 µm，与超声角膜测厚仪的下、上限 95%LoA 为-25.9~25.5 µm。扫描 slit topography 的声学因子为 0.94。
在 PRK 治疗后的晚期，Scheimpflug 成像测量的 CCT 比超声角膜测厚仪或扫描 slit topography 厚。应用校正因子后，Scheimpflug 测量值与超声角膜测厚仪值更接近，与扫描 slit topography 相比一致性更好。
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