Gyurjyan H V, Tucker-Schwartz J M, Gillies G T, Mahapatra S
University of Virginia, Department of Biomedical Engineering, PO Box 800759, Charlottesville, VA 22908, USA.
J Med Eng Technol. 2010 Feb;34(2):134-40. doi: 10.3109/03091900903428340.
We have developed a prototype, in vitro anthropomorphic model for simulating pressure-guided, subxiphoid access procedures done to enable minimally invasive epicardial cardiac procedures including treatments for ventricular tachycardia. Life-size replicas of the heart and lungs were modelled using anatomically accurate surrogates. The dynamic pressure-frequency profiles of simulated pericardial fluid surrounding the water-pumped replica heart were measured and validated against previously acquired human intrapericardial pressure observations (Pearson's r = 0.88, p < 0.001). In replicating access procedures for approaching and entering the pericardial space, the system produced physiologically appropriate pressure measurements at each intermediate point along the needle's insertion pathway. Details of construction and performance are presented and discussed.
我们已经开发出一种体外人体模型原型，用于模拟在压力引导下的剑突下穿刺入路操作，以实现微创心外膜心脏手术，包括室性心动过速的治疗。使用解剖学上精确的替代物对心脏和肺的实物大小复制品进行建模。测量了围绕水泵驱动的复制品心脏的模拟心包液的动态压力-频率曲线，并与先前获得的人体心包内压力观测值进行了验证（皮尔逊相关系数r = 0.88，p < 0.001）。在复制接近和进入心包腔的穿刺入路操作时，该系统在沿针插入路径的每个中间点都产生了生理上合适的压力测量值。本文介绍并讨论了该模型的构建细节和性能。
