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曲安奈德注射液治疗持续性非典型特发性眼眶炎症。

Triamcinolone acetonide injection for persistent atypical idiopathic orbital inflammation.

作者信息

Skaat Alon, Rosen Nachum, Rosner Mordechai, Schiby Ginette, Simon Guy J Ben

机构信息

Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel.

出版信息

Orbit. 2009;28(6):401-3. doi: 10.3109/01676830903071208.

DOI:10.3109/01676830903071208
PMID:19929669
Abstract

PURPOSE

To report a patient with atypical idiopathic orbital inflammation who was successfully treated with intra-orbital injections of triamcinolone acetonide.

METHODS

Interventional case report and literature review.

MAIN OUTCOME MEASURES

Resolution of orbital inflammation.

RESULTS

A 71-year-old female with right orbital mass and conjunctival inflammation underwent orbital biopsy that was consistent with the diagnosis of atypical idiopathic orbital inflammation. Inflammation has deteriorated despite oral steroids. The patient underwent two additional orbital biopsies that confirmed the initial diagnosis. Intra-orbital injections of triamcinolone acetonide resulted in significant improvement and cessation of active inflammation.

CONCLUSIONS

Intra-orbital injections of triamcinolone acetonide may be an effective alternative in patients with atypical idiopathic orbital inflammation unresponsive to systemic steroids.

摘要

目的

报告一例非典型特发性眼眶炎症患者,经眶内注射曲安奈德成功治疗。

方法

介入性病例报告及文献综述。

主要观察指标

眼眶炎症消退情况。

结果

一名71岁女性,有右侧眼眶肿物及结膜炎症,接受眼眶活检,结果符合非典型特发性眼眶炎症的诊断。尽管使用了口服类固醇药物,炎症仍恶化。患者又接受了两次眼眶活检,证实了最初的诊断。眶内注射曲安奈德使炎症显著改善并停止了活动性炎症。

结论

对于对全身类固醇药物无反应的非典型特发性眼眶炎症患者,眶内注射曲安奈德可能是一种有效的替代治疗方法。

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引用本文的文献

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Nonspecific Orbital Inflammation (NSOI): Unraveling the Molecular Pathogenesis, Diagnostic Modalities, and Therapeutic Interventions.非特异性眼眶炎症(NSOI):解析分子发病机制、诊断方式和治疗干预。
Int J Mol Sci. 2024 Jan 26;25(3):1553. doi: 10.3390/ijms25031553.
2
Intraorbital corticosteroid injection for orbital reactive lymphoid hyperplasia.眶内皮质类固醇注射治疗眼眶反应性淋巴组织增生。
Eye (Lond). 2013 Apr;27(4):561-3. doi: 10.1038/eye.2012.288. Epub 2013 Jan 25.