天然香豆素类化合物作为一类新型的神经保护剂。

Natural coumarins as a novel class of neuroprotective agents.

机构信息

Dipartimento di Scienze del Farmaco, Università "G. D'Annunzio" di Chieti-Pescara, Chieti Scalo, Italy.

出版信息

Mini Rev Med Chem. 2009 Oct;9(11):1262-71. doi: 10.2174/138955709789878141.

PMID:19929804

Abstract

Neurodegenerative disorders are a heterogeneous group of diseases and are among the most invaliding syndromes for humans. The aim of this manuscript is to review what has been reported so far in the literature about coumarins as a novel class of pharmacologically active compounds in chemoprevention and/or therapy of these diseases.

摘要

神经退行性疾病是一组异质性疾病，是对人类危害最大的综合征之一。本文旨在综述迄今为止文献中关于香豆素作为一类新型具有药理活性的化合物在这些疾病的化学预防和/或治疗中的作用。