Department of Medicine, Division of Pulmonary and Critical Care, Oregon Health and Science University, Portland, OR 97239, USA.
Crit Care. 2009;13(6):1003. doi: 10.1186/cc8113. Epub 2009 Nov 11.
Whereas the pulmonary artery catheter (PAC) is still widely used in guiding assessment and treatment of heart failure, controversy surrounding its safety and efficacy has prompted development of newer, less invasive techniques. For these purposes, the transpulmonary thermodilution technique allows assessment of preload, cardiac output, filling volumes, and metrics of contractility without the need to pass a catheter through the right heart. In a previous issue of Critical Care, Ritter and colleagues compare metrics of transpulmonary thermodilution with the PAC in patients with acute heart failure and severe sepsis. The results add to a growing body of evidence that the PAC adds little to information attainable by less invasive methods in many conditions, including acute heart failure. Whether newer devices improve outcome needs to be tested in well-controlled prospective trials.
虽然肺动脉导管(PAC)仍广泛用于指导心力衰竭的评估和治疗,但围绕其安全性和有效性的争议促使开发了更新、侵入性更小的技术。为此,经肺热稀释技术允许评估前负荷、心输出量、充盈量和收缩力指标,而无需将导管穿过右心。在《危重病医学》的前一期中,Ritter 及其同事比较了急性心力衰竭和严重脓毒症患者经肺热稀释与 PAC 的各项指标。这些结果进一步证明,在许多情况下,包括急性心力衰竭,PAC 对通过侵入性较小的方法获得的信息几乎没有增加。需要在精心设计的前瞻性试验中检验新型设备是否能改善预后。