Naik Veena, Arsenovic Nebojsa, Reed Malcolm
Department of Cellular Pathology, Pathlinks Pathology Services, Lincoln County Hospital, Lincoln, United Kingdom.
Dermatol Online J. 2009 Sep 15;15(9):6.
Eccrine angiomatous hamartoma (EAH) is a rare, benign cutaneous tumor characterized by proliferation of the eccrine gland elements closely associated with capillary angiomatosis and proliferation of other dermal elements, such as adipose tissue, hair and epidermis. Patients usually present with a solitary nodule on the extremities appearing at birth or during the prepubertal years. However multifocal lesions or late onset of this condition may occur. Eccrine angiomatous hamartoma is usually sporadic, but one familial case of the multifocal variant has been reported. The clinical presentation ranges from a simple angiomatous nodule to erythematous--purpuric plaques. Eccrine angiomatous hamartoma is generally asymptomatic but may occasionally be associated with pain and hyperhidrosis. We report a rare case of the multifocal variant of EAH in a 13-year-old girl, with histological features suggesting trauma. Clinically, this condition must be differentiated from other angiomatoses and a definitive diagnosis is based upon histology. Eccrine angiomatous hamartoma is a benign slowly growing lesion for which aggressive treatment is not indicated. Simple excision is reserved for painful or cosmetically disfiguring examples.
小汗腺血管瘤性错构瘤（EAH）是一种罕见的良性皮肤肿瘤，其特征是小汗腺成分增生，并与毛细血管血管瘤病以及其他真皮成分（如脂肪组织、毛发和表皮）的增生密切相关。患者通常在出生时或青春期前出现四肢单发结节。然而，也可能发生多灶性病变或发病较晚的情况。小汗腺血管瘤性错构瘤通常为散发性，但有一例多灶性变异型的家族病例报道。临床表现从单纯的血管瘤性结节到红斑 - 紫癜性斑块不等。小汗腺血管瘤性错构瘤一般无症状，但偶尔可能伴有疼痛和多汗症。我们报告了一例13岁女孩的罕见多灶性变异型EAH病例，其组织学特征提示有创伤。临床上，这种疾病必须与其他血管瘤病相鉴别，确诊依据组织学检查。小汗腺血管瘤性错构瘤是一种良性的生长缓慢的病变，无需进行积极治疗。对于疼痛或影响美观的病例，可考虑单纯切除。
