特比萘芬诱发的急性泛发性脓疱性皮病（AGEP）对大剂量静脉注射皮质类固醇有反应。
Terbinafine-induced acute generalized exanthematous pustulosis (AGEP) responsive to high dose intravenous corticosteroid.
作者信息
Ibrahimi Omar A, Gunawardane Nilanthi, Sepehr Alireza, Reynolds Rachel V
机构信息
Harvard Medical School, Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA.
出版信息
Dermatol Online J. 2009 Sep 15;15(9):8.
PMID:19930995
Abstract
Acute generalized exanthematous pustulosis (AGEP) is a febrile pustular drug eruption. Terbinafine, an allylamine fungicidial agent, is the most common anti-mycotic associated with AGEP. Here, we report a case of terbinafine-induced AGEP that was recalcitrant to oral corticosteroid but responsive to high-dose intravenous corticosteroid.
摘要
急性泛发性脓疱性皮病（AGEP）是一种发热性脓疱性药疹。特比萘芬是一种烯丙胺类杀真菌剂，是与AGEP相关的最常见抗真菌药。在此，我们报告一例特比萘芬诱发的AGEP，该病例对口服糖皮质激素治疗无效，但对大剂量静脉注射糖皮质激素治疗有反应。
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