Thoracic Surgery Unit, Second University of Naples, Naples, Italy.
Ann Thorac Surg. 2009 Dec;88(6):2001-4. doi: 10.1016/j.athoracsur.2009.05.042.
Intrathoracic extramedullary hematopoiesis (EMH), the formation of apparently normal blood cells outside the confines of the bone marrow, is an uncommon but well-defined entity. It is usually associated with hematologic disorders and located in the lower paravertebral sulci or rarely in the pleura. We report a case of EMH, which presented in a patient without hematologic disorders and was manifested as an anterior mediastinal mass. The first interesting aspect of our case was that EMH occurred in a patient with normal laboratory findings and no past medical history of anemia. The second remarkable characteristic was that EMH manifested as an anterior mediastinal mass, mimicking a neoplastic lesion. Definitive diagnosis of EMH was established by a video-assisted thoracoscopic surgical biopsy. In light of this diagnosis, no further surgical procedure was carried out.
胸内髓外造血(EMH),即骨髓外正常血细胞的形成,是一种不常见但明确的病症。它通常与血液疾病有关,位于下脊柱旁沟,或很少位于胸膜。我们报告了一例 EMH 病例,患者无血液疾病,表现为前纵隔肿块。我们病例的第一个有趣之处是,EMH 发生在实验室检查正常且无贫血病史的患者中。第二个显著特征是 EMH 表现为前纵隔肿块,类似于肿瘤病变。通过胸腔镜手术活检明确了 EMH 的诊断。鉴于此诊断,未进行进一步的手术。