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后纵隔巨大髓外造血肿块:一例报告

Huge extramedullary hematopoiesis mass in the posterior mediastinum: a case report.

作者信息

Junjun Zhao, Lingjun Dong, Zhifeng Ma, Chu Zhang, Haiyong Wang

机构信息

Department of Thoracic Surgery, Shaoxing People's Hospital, Shaoxing, Zhejiang, China.

出版信息

Front Oncol. 2024 Dec 13;14:1489785. doi: 10.3389/fonc.2024.1489785. eCollection 2024.

Abstract

BACKGROUND

Extramedullary hemopoiesis (EMH) is a rare condition characterized by abnormal blood cell production outside the bone marrow, commonly occurring in the liver, spleen, lymph nodes, and less frequently in the mediastinum.

CASE PRESENTATION

This case involves a 68-year-old male patient who was found to have a posterior mediastinal mass upon examination. A surgical biopsy was performed, and pathological examination confirmed it to be extramedullary hemopoiesis (EMH). Further investigation revealed that the patient also suffered from hemolytic anemia.

CONCLUSIONS

The report presents a case of a large posterior mediastinal mass, which was confirmed to be extramedullary hemopoiesis (EMH) upon surgical pathology. It is challenging to differentiate posterior mediastinal tumors from EMH, and the possibility of EMH should be considered in patients with posterior mediastinal masses that have similar CT findings and laboratory test results.

摘要

背景

髓外造血(EMH)是一种罕见的病症,其特征为骨髓外异常血细胞生成,常见于肝脏、脾脏、淋巴结,较少见于纵隔。

病例介绍

该病例为一名68岁男性患者,检查发现后纵隔有一肿块。进行了手术活检,病理检查证实为髓外造血(EMH)。进一步检查发现该患者还患有溶血性贫血。

结论

本报告呈现了一例后纵隔巨大肿块病例,手术病理证实为髓外造血(EMH)。区分后纵隔肿瘤与EMH具有挑战性,对于具有相似CT表现和实验室检查结果的后纵隔肿块患者,应考虑EMH的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/11671360/cc8185950f74/fonc-14-1489785-g001.jpg

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