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累及肺动脉的肺外髓外造血。

Pulmonary extramedullary hematopoiesis involving the pulmonary artery.

作者信息

Monga Varun, Silverman Margarida

机构信息

Division of Hematology/Oncology and Bone Marrow Transplantation, University of Iowa Hospitals and Clinics , Iowa City, IA, USA.

出版信息

Hematol Rep. 2015 Mar 24;7(1):5714. doi: 10.4081/hr.2015.5714. eCollection 2015 Feb 24.

Abstract

Extramedullary hematopoiesis (EMH) occurs as a complication of hematologic disorders such as myelofibrosis, sickle cell anemia and thalassemia. The extramedullary tissue usually involves liver, spleen and lymph nodes, less frequently the chest. We present a recent case of a man with myeloproliferative neoplasm who developed pulmonary hemorrhage secondary to EMH in the lung and pulmonary artery. Radiation therapy was considered the best approach, but it didn't work and the patient died a week after radiation therapy was completed. We also review herein the present literature.

摘要

髓外造血(EMH)是诸如骨髓纤维化、镰状细胞贫血和地中海贫血等血液系统疾病的一种并发症。髓外组织通常累及肝脏、脾脏和淋巴结,累及胸部的情况较少见。我们报告了一例近期的病例,一名患有骨髓增殖性肿瘤的男性因肺部和肺动脉的髓外造血继发肺出血。放射治疗被认为是最佳治疗方法,但未起作用,患者在放疗结束一周后死亡。我们在此还对当前的文献进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5256/4378208/1e29b09826d0/hr-2015-1-5714-g001.jpg

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