肺隔离症伴血清糖类抗原 19-9 显著升高。

Intralobar pulmonary sequestration associated with marked elevation of serum carbohydrate antigen 19-9.

机构信息

Department of Surgery, Oami Hospital, Oamishirasato, Japan.

出版信息

Ann Thorac Surg. 2009 Dec;88(6):2010-1. doi: 10.1016/j.athoracsur.2009.05.017.

DOI:10.1016/j.athoracsur.2009.05.017

PMID:19932280

Abstract

This report describes a 62-year-old man who experienced elevated serum carbohydrate antigen 19-9 (CA19-9) levels (>500 U/mL) for 4 years, and was finally diagnosed with right intralobar pulmonary sequestration. Surgery confirmed the presence an aberrant artery arising from the descending thoracic aorta and entering the right lower lobe basal segment. Immunohistochemistry demonstrated markedly positive staining of CA19-9 in the ciliated cylindrical epithelia, alveoli, and mucus in the cysts. After pulmonary resection, CA19-9 levels decreased to within a normal range. Therefore, the cause of the elevated serum CA19-9 levels in this case was almost certainly due to intralobar pulmonary sequestration.

摘要

本报告描述了一位 62 岁男性，其血清碳水化合物抗原 19-9（CA19-9）水平升高（>500 U/mL）已有 4 年，并最终被诊断为右叶内型肺隔离症。手术证实存在一条异常动脉，发自降主动脉并进入右下叶基底段。免疫组化显示囊腔内的纤毛柱状上皮、肺泡和黏液中 CA19-9 呈明显阳性染色。肺切除术后，CA19-9 水平降至正常范围内。因此，本例血清 CA19-9 水平升高的原因几乎可以肯定是由于右叶内型肺隔离症。