叶内型肺隔离症伴血清CA19-9和CA125升高。

Intralobar pulmonary sequestration presenting increased serum CA19-9 and CA125.

作者信息

Yagyu Hisanaga, Adachi Hideki, Furukawa Kinya, Nakamura Hiroyuki, Sudoh Akihiko, Oh-ishi Shuuji, Tsuchida Fumihiro, Kishi Kouji, Saitou Makoto, Matsuoka Takeshi

机构信息

Fifth Department of Internal Medicine, Tokyo Medical University, Inashiki-gun, Ibaraki.

出版信息

Intern Med. 2002 Oct;41(10):875-8. doi: 10.2169/internalmedicine.41.875.

DOI:10.2169/internalmedicine.41.875

PMID:12413014

Abstract

A 39-year-old man was admitted to our hospital for further evaluation of a consolidated shadow and clarification of the cause of serum tumor marker elevation (CA19-9 496.2 U/ml, CA125 160.6 U/ml). Chest computed tomography revealed a well-defined homogeneous nodule in the left S(10). Angiography showed one aberrant artery, branching from the ascending aorta. Intralobar pulmonary sequestration was diagnosed and the sequestrated lung was resected. Microscopic findings of the sequestrated lung showed a mucus-containing cystically dilated bronchus, which was covered with ciliated cylindrical epithelium. Immunohistochemical staining showed positive staining for CA19-9 and CA125 in both the ciliated cylindrical epithelium and mucus. Serum values of tumor markers returned to their normal range after surgery.

摘要

一名39岁男性因肺部实变影进一步评估及血清肿瘤标志物升高（CA19-9 496.2 U/ml，CA125 160.6 U/ml）原因待查入住我院。胸部计算机断层扫描显示左肺下叶背段（S10）有一个边界清晰的均匀结节。血管造影显示一条异常动脉，从升主动脉分支。诊断为肺叶内型肺隔离症，并切除了隔离肺。隔离肺的显微镜检查显示一个含有黏液的囊状扩张支气管，其被覆纤毛柱状上皮。免疫组化染色显示纤毛柱状上皮和黏液中CA19-9和CA125均呈阳性染色。术后肿瘤标志物血清值恢复至正常范围。