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使用速即纱贴片修复血管成形术后冠状动脉穿孔

Repair of coronary artery perforation following angioplasty using TachoSil patches.

作者信息

Celiento Michele, Scioti Giovanni, Pratali Stefano, Bortolotti Uberto

机构信息

Section of Cardiac Surgery, Cardiac Thoracic and Vascular Department, University of Pisa Medical School, 56124 Pisa, Italy.

出版信息

Interact Cardiovasc Thorac Surg. 2010 Feb;10(2):328-30. doi: 10.1510/icvts.2009.225334. Epub 2009 Nov 19.

DOI:10.1510/icvts.2009.225334
PMID:19933239
Abstract

Coronary perforation is a rare complication of percutaneous interventional procedures, occurring in 0.2-3% of procedures, which may require emergency coronary bypass surgery. We describe here an alternative method to deal with such complication, which proved effective in a patient with active bleeding from the left anterior descending (LAD) coronary artery. By temporary pressing on beating heart patches of TachoSil, a sponge impregnated with human fibrinogen and thrombin, on the bleeding site, complete and stable hemostasis was achieved.

摘要

冠状动脉穿孔是经皮介入手术中一种罕见的并发症,发生率为0.2%-3%,可能需要进行急诊冠状动脉搭桥手术。我们在此描述一种处理此类并发症的替代方法,该方法在一名左前降支(LAD)冠状动脉活动性出血的患者中被证明是有效的。通过在跳动的心脏上临时按压含有人类纤维蛋白原和凝血酶的海棉状速即纱贴片于出血部位,实现了完全且稳定的止血。

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引用本文的文献

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TachoSil for postinfarction ventricular free wall rupture.速即纱用于心肌梗死后心室游离壁破裂。
Interact Cardiovasc Thorac Surg. 2012 Jun;14(6):866-7. doi: 10.1093/icvts/ivs085. Epub 2012 Mar 14.
2
The long term immunological response of swine after two exposures to a salmon thrombin and fibrinogen hemostatic bandage.猪两次接触鲑鱼凝血酶和纤维蛋白原止血绷带后的长期免疫反应。
Biologicals. 2010 Nov;38(6):619-28. doi: 10.1016/j.biologicals.2010.07.001. Epub 2010 Aug 11.