Jules Stein Eye Institute, David Geffen/UCLA School of Medicine, Los Angeles, California 90095, USA.
Retina. 2009 Oct;29(9):1340-5. doi: 10.1097/IAE.0b013e3181b0da88.
To compare optical coherence tomography with fluorescein angiography in 11 patients (21 eyes) with central foveal damage from solar retinopathy.
Retrospective, observational case series of 11 patients with solar retinopathy. Dilated funduscopic examination was performed as well as photographic, fluorescein angiography, optical coherence tomography, and Humphrey visual field assessment.
Significant foveal pathology was identified in each of the 21 eyes (11 patients). Visual acuity in affected eyes ranged from 20/25 to 20/200. Optical coherence tomography demonstrated foveal atrophy associated with a characteristic defect at the level of the inner and outer segment junction of the photoreceptors in all 21 affected eyes, whereas fluorescein angiography identified classic window defects in 19 eyes (10 of 11 patients). There was a modest correlation between foveal thickness and visual acuity.
Fluorescein angiography did not detect lesions characteristic of solar retinopathy in all patients with a definitive history of sungazing and visual loss. Conversely, optical coherence tomography did detect significant foveal atrophy in all affected eyes and a characteristic defect at the photoreceptor-retinal pigment epithelium junction. Optical coherence tomography improves the diagnosis and assessment of the degree and nature of foveal damage in patients with solar retinopathy and may be an important tool in identifying foveal damage not detected by standard fluorescein angiography.
比较光学相干断层扫描（OCT）与荧光素血管造影（FA）在 11 例（21 只眼）由太阳视网膜病变引起的中心凹性损害中的应用。
回顾性观察性病例系列研究，纳入 11 例太阳视网膜病变患者。进行了散瞳眼底检查以及照相、荧光素血管造影、OCT 和 Humphrey 视野评估。
21 只眼中（11 例患者）均发现明显的中心凹病变。受影响眼的视力从 20/25 到 20/200 不等。OCT 在所有 21 只受影响眼中均显示出与光感受器内外节交界处特征性缺陷相关的中心凹萎缩，而 FA 在 19 只眼中（11 例患者中的 10 例）发现了典型的窗样缺损。中心凹厚度与视力之间存在适度的相关性。
荧光素血管造影未能在所有有明确直视太阳史和视力丧失的患者中检测到典型的太阳视网膜病变病变。相反，OCT 在所有受影响的眼中均检测到明显的中心凹萎缩和光感受器-视网膜色素上皮交界处的特征性缺陷。OCT 提高了太阳视网膜病变患者中心凹损伤的诊断和严重程度评估，并可能成为识别标准荧光素血管造影未检测到的中心凹损伤的重要工具。
