Division of Infectious Diseases, Nationwide Children's Hospital, Columbus, OH 43205, USA.
Pediatr Infect Dis J. 2010 Mar;29(3):274-5. doi: 10.1097/INF.0b013e3181bdbd88.
Current Centers for Disease Control and Prevention (CDC) recommendations suggest all pregnant women have human immunodeficiency virus (HIV) antibody testing early in pregnancy. For women with specific identified risks for HIV-1 infection, the CDC recommends repeat testing in the third trimester. We report 3 cases of infants perinatally infected with HIV-1 whose mothers tested negative for HIV-1 during the first trimester of pregnancy. Because they were not considered to be "high risk" for HIV-1 infection, they did not have a third trimester HIV test. These cases suggest that repeat HIV antibody testing may be necessary to avoid cases of perinatal transmission that might be prevented with antiretroviral treatment during pregnancy.
目前，疾病控制与预防中心（CDC）的建议是所有孕妇在怀孕早期进行人类免疫缺陷病毒（HIV）抗体检测。对于具有特定 HIV-1 感染风险的女性，CDC 建议在第三孕期重复检测。我们报告了 3 例婴儿在围产期感染 HIV-1 的病例，其母亲在妊娠早期 HIV-1 检测呈阴性。由于他们被认为不是 HIV-1 感染的“高危”人群，因此他们没有进行第三孕期 HIV 检测。这些病例表明，重复进行 HIV 抗体检测可能是必要的，以避免可能因孕期抗逆转录病毒治疗而预防的围产期传播病例。
