Section of Ophthalmology, Department of Head and Neck Surgery, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
Ophthalmic Plast Reconstr Surg. 2009 Nov-Dec;25(6):426-9. doi: 10.1097/IOP.0b013e3181b78989.
To report the use of AlloDerm for reconstruction of large upper eyelid defects in cancer patients.
The clinical records of all patients who had AlloDerm as part of their upper eyelid reconstruction between July 2005 and July 2006 at a single institution were reviewed. Functional and cosmetic outcomes and postoperative complications were assessed.
Two patients had recurrent sebaceous gland carcinoma, 2 had melanoma, and 1 had squamous cell carcinoma. The upper eyelid defect involved the full thickness and entire width of the upper eyelid in 4 patients and full thickness and two thirds of the upper eye eyelid in 1 patient. The reconstructive procedure included a modified Cutler-Beard procedure using AlloDerm as the posterior lamellar sandwich graft in all 5 patients. One patient had early postoperative adjuvant radiation therapy to the upper eyelid. Three patients had excellent functional and cosmetic outcome; 2 patients had satisfactory outcomes. Two patients had residual exposure keratopathy. Allergic reaction to AlloDerm, infectious transmission, and immunologic rejection were not encountered at the time of this report (mean follow-up time = 13 months).
AlloDerm can be used as an alternative sandwich graft material to replace the tarsus for reconstruction of large upper eyelid defects using a modified Cutler-Beard procedure.
报告使用 AlloDerm 重建癌症患者的大面积上眼睑缺损。
回顾了 2005 年 7 月至 2006 年 7 月在一家机构中使用 AlloDerm 作为上眼睑重建一部分的所有患者的临床记录。评估了功能和美容结果以及术后并发症。
2 例患者为复发性皮脂腺癌，2 例为黑色素瘤，1 例为鳞状细胞癌。4 例患者的上眼睑缺损累及上眼睑的全层和整个宽度，1 例患者的上眼睑缺损累及全层和三分之二的上眼睑。重建程序包括在所有 5 例患者中使用 AlloDerm 作为后板层三明治移植物的改良 Cutler-Beard 手术。1 例患者在上眼睑接受早期术后辅助放疗。3 例患者的功能和美容效果良好；2 例患者的结果满意。2 例患者仍存在暴露性角膜炎。在本报告（平均随访时间为 13 个月）时，未发现对 AlloDerm 的过敏反应、传染性传播和免疫排斥反应。
AlloDerm 可用作替代的三明治移植物材料，用于使用改良的 Cutler-Beard 手术重建大面积上眼睑缺损。
