Division of Nephrology, Mount Sinai School of Medicine, Recanati/Miller Transplantation Institute, New York, NY 10029, USA.
Transplantation. 2009 Nov 27;88(10):1157-8. doi: 10.1097/TP.0b013e3181bdbf92.
Chronic allograft injury remains the leading cause of graft loss despite improvements in immunosuppression, clinical risk stratification, and state-of-the-art antibody testing. Emerging results indicate that T-cell immune monitoring by cytokine enzyme-linked immunosorbent spot, as part of a comprehensive risk assessment platform, has the potential to guide decision making and improve outcomes after transplantation.
尽管免疫抑制、临床风险分层和最先进的抗体检测都有所改进，但慢性移植物损伤仍然是导致移植物丢失的主要原因。新出现的结果表明，细胞因子酶联免疫斑点法的 T 细胞免疫监测作为综合风险评估平台的一部分，具有指导决策和改善移植后结局的潜力。
