Department of Neonatology, University Medical Center, Utrecht, The Netherlands.
Pediatr Infect Dis J. 2010 Apr;29(4):364-5. doi: 10.1097/INF.0b013e3181c6e60f.
Data of 11 infants (median gestational age and birth weight 30 weeks and 1520 g, respectively) with severe human rhinovirus infection (HRV) are described. Nine of 11 (82%) were preterm infants and 7 of these 9 (78%) became infected during their stay in the neonatal intensive care unit. All infants presented with respiratory distress and all needed respiratory support for a median of 6 days. Radiologic findings included perihilar streakiness, atelectasis, focal consolidation, and hyperinflation. The diagnosis of HRV infection was made by real-time polymerase chain reaction in nasopharyngeal aspirate. All infants recovered from their HRV infection. HRV can cause severe disease in preterm infants requiring respiratory support.
现描述 11 例严重人鼻病毒（HRV）感染婴儿的数据。11 例患儿中，中位胎龄和出生体重分别为 30 周和 1520 克，9 例（82%）为早产儿，其中 9 例（78%）在新生儿重症监护病房（NICU）期间感染。所有患儿均有呼吸窘迫，中位需呼吸支持 6 天。影像学表现包括肺门条纹影、肺不张、局灶性实变和过度充气。HRV 感染的诊断通过鼻咽抽吸物实时聚合酶链反应（PCR）进行。所有患儿均从 HRV 感染中恢复。HRV 可引起需要呼吸支持的早产儿发生严重疾病。
