Khan Tahir H, Farooqui Falahat A, Niazi Khusrow
Hospitalist / Instructor of Medicine, Emory University Dept of Medicine, Emory Crawford Long Hospital, 550 Peachtree St, MOT 6th Fl Rm 4307, Atlanta, GA 30308, USA.
Curr Cardiol Rev. 2008 May;4(2):101-6. doi: 10.2174/157340308784245810.
Ankle brachial index (ABI) has been utilized in the management of peripheral arterial disease (PAD).ABI is a surrogate marker of atherosclerosis and recent studies indicate its utility as a predictor of future cardiovascular disease and all-cause mortality. Even so, this critical test is underutilized. The purpose of this review is to summarize available evidence associated with ABI methodology variances, ABI usage in the treatment of PAD, and ABI efficacy in predicting cardiovascular disease. This review further evaluates how ABI is used in the prognosis and follow-up of lower extremity arterial disease.We reviewed the most current American College of Cardiology guidelines for the management of PAD, the Trans Atlantic Intersociety Consensus (TASC) working group recommendations, and searched the Medline for the following words: ankle brachial index, ABI sensitivity and specificity, and peripheral arterial disease.The ABI is a simple, noninvasive clinical test that should not only be applied to diagnose PAD, but also to provide important prognostic information about future cardiovascular events. Although the ABI has been employed in clinical practice for some time, our review of various studies reveals a lack of standardization regarding both the method of measuring ABI and the cutoff point for abnormal ABI. It is extremely important that we understand all aspects of this crucial test, as it is now being recommended as part of a patient's routine health risk assessment.
踝臂指数(ABI)已被用于外周动脉疾病(PAD)的管理。ABI是动脉粥样硬化的替代标志物,最近的研究表明其可作为未来心血管疾病和全因死亡率的预测指标。即便如此,这项关键检查仍未得到充分利用。本综述的目的是总结与ABI方法差异、ABI在PAD治疗中的应用以及ABI预测心血管疾病的疗效相关的现有证据。本综述还进一步评估了ABI在下肢动脉疾病的预后和随访中的应用情况。我们查阅了美国心脏病学会最新的PAD管理指南、跨大西洋两岸社会共识(TASC)工作组的建议,并在Medline中搜索了以下词汇:踝臂指数、ABI的敏感性和特异性以及外周动脉疾病。ABI是一项简单的非侵入性临床检查,不仅应用于诊断PAD,还应为未来心血管事件提供重要的预后信息。尽管ABI已在临床实践中应用了一段时间,但我们对各项研究的综述显示,在ABI的测量方法和异常ABI的临界值方面均缺乏标准化。了解这项关键检查的各个方面极为重要,因为现在它被推荐作为患者常规健康风险评估的一部分。