天然产物的成像质谱分析

Imaging mass spectrometry of natural products.

作者信息

Esquenazi Eduardo, Yang Yu-Liang, Watrous Jeramie, Gerwick William H, Dorrestein Pieter C

机构信息

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, USA.

出版信息

Nat Prod Rep. 2009 Dec;26(12):1521-34. doi: 10.1039/b915674g. Epub 2009 Nov 9.

DOI:10.1039/b915674g

PMID:19936384

Abstract

This Highlight article describes three different imaging mass spectrometry (IMS) approaches, MALDI, DESI and SIMS and their recent applications in the analysis of natural products. IMS has opened up a new avenue for establishing the functional roles of natural products.

摘要

这篇重点文章描述了三种不同的成像质谱（IMS）方法，即基质辅助激光解吸电离（MALDI）、解吸电喷雾电离（DESI）和二次离子质谱（SIMS）及其在天然产物分析中的最新应用。成像质谱为确定天然产物的功能作用开辟了一条新途径。