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LL-37的化学与生物学特性

The chemistry and biology of LL-37.

作者信息

Burton Matthew F, Steel Patrick G

机构信息

Centre for Bioactive Chemistry, Department of Chemistry, University of Durham, Science Laboratory, South Road, Durham, DH1 3LE, UK.

出版信息

Nat Prod Rep. 2009 Dec;26(12):1572-84. doi: 10.1039/b912533g. Epub 2009 Oct 1.

DOI:10.1039/b912533g
PMID:19936387
Abstract

LL-37 is a human host defence peptide that has a wide range of biological functions, including antimicrobial and immunomodulatory properties. This review summarises how molecular structure influences the balance between the immunomodulatory and antimicrobial functions of LL-37.

摘要

LL-37是一种具有广泛生物学功能的人体防御肽，包括抗菌和免疫调节特性。本综述总结了分子结构如何影响LL-37免疫调节和抗菌功能之间的平衡。

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