Department of Pediatrics and Child Health, The Aga Khan University Hospital, Karachi.
Indian J Pediatr. 2009 Dec;76(12):1227-30. doi: 10.1007/s12098-009-0258-z.
To determine the frequency and associated risk factors of hypomagnesemia in pediatric intensive care unit on admission in a developing country.
It is a retrospective chart review of 179 children aged 1 mo - 15yr admitted in Pediatric Intensive Care Unit of our university during 18 months and recorded serum Mg level on admission. Patients were divided into two groups according to their Mg level (Normo-magnesemic and Hypomagnesemic) and their p-value, crude and adjusted odds ratios (AoR) were calculated.
Upon admission in PICU 79(44%) patients were found hypomagnesemia. There was no difference in age and gender between two groups. The important risk factors identified were age greater than one yr (p 0.05, AOR 3.71), sepsis (p 0.03, AOR 3.11), hypokalemia (p 0.06, AOR 1.8), hypocalcemia (p 0.05, AOR 1.6), diuretic use (p 0.05, AOR 1.37), Aminoglycoside use (p 0.003, AOR 3.12), and hospitalization greater than five days (p 0.03, AOR 1.71). Those with normo-magnesemic had higher mortality rate (32/100 or 32%) than those with hypomagnesemia (22/79 or 27.8%).
The present finding indicates that hypomagnesemia is a common among PICU patients and is influenced by several factors.
在发展中国家，确定儿科重症监护病房入院时低镁血症的频率及其相关危险因素。
这是对 18 个月内在我们大学儿科重症监护病房入院的 179 名 1 个月至 15 岁儿童的回顾性图表审查，并记录入院时的血清 Mg 水平。根据镁水平（正常镁血症和低镁血症）将患者分为两组，并计算其 p 值、粗比值比（AoR）和调整比值比（AoR）。
在 PICU 入院时，发现 79 名（44%）患者存在低镁血症。两组间的年龄和性别无差异。确定的重要危险因素是年龄大于 1 岁（p<0.05，AoR 3.71）、败血症（p<0.03，AoR 3.11）、低钾血症（p<0.06，AoR 1.8）、低钙血症（p<0.05，AoR 1.6）、利尿剂使用（p<0.05，AoR 1.37）、氨基糖苷类药物使用（p<0.003，AoR 3.12）和住院时间大于 5 天（p<0.03，AoR 1.71）。正常镁血症患者的死亡率（32/100 或 32%）高于低镁血症患者（22/79 或 27.8%）。
本研究表明，低镁血症在儿科重症监护病房患者中很常见，受多种因素影响。
