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[维斯纳病毒诱导培养的绵羊脉络丛细胞发生细胞融合的超微结构特征]

[Ultrastructural aspects of the cell fusion induced by Visna virus on sheep choroid plexus cell in culture].

作者信息

Pautrat G, Benkoel L, de tmicco P, Tamalet J

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Sep 26;285(6):733-6.

PMID:199372
Abstract

Sheep choroid plexus cells infected with low multiplicities of infection of Visna Virus were stellate and had long and thin processes containing filaments and forming cytoplasmic bridges between adjacent cells. Enlargement of the bridges resulted in the formation of multinucleated cells. Some glycoproteins were clustered on filaments outside the cell. The cytoplasmic changes showed : an intensive protein synthesis; numerous mitochondria closely associated with filaments and some lysosomes and numerous vesicules near the plasma membrane.

摘要

感染低感染复数维斯纳病毒的绵羊脉络丛细胞呈星状,有细长的突起,内含细丝,并在相邻细胞间形成细胞质桥。桥的增大会导致多核细胞的形成。一些糖蛋白聚集在细胞外的细丝上。细胞质变化表现为:蛋白质合成活跃;大量线粒体与细丝紧密相连,还有一些溶酶体以及靠近质膜的大量小泡。

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