Maloney-Wilensky Eileen, Le Roux Peter
Clinical Research Division, Department of Neurosurgery, University of Pennsylvania, 330 S. 9th Street, Philadelphia, PA 19107, USA.
Childs Nerv Syst. 2010 Apr;26(4):419-30. doi: 10.1007/s00381-009-1037-x.
Secondary neuronal injury is implicated in poor outcome after acute neurological insults. Outcome can be improved with protocol-driven therapy. These therapies have largely been based on monitoring and control of intracranial pressure and the maintenance of an adequate cerebral perfusion pressure.
In recent years, brain tissue oxygen partial pressure (PbtO2) monitoring has emerged as a clinically useful modality and a complement to intracranial pressure monitors. This review examines the physiology of PbtO2 monitors and practical aspects of their use.
继发性神经元损伤与急性神经损伤后的不良预后有关。通过方案驱动治疗可改善预后。这些治疗主要基于颅内压监测与控制以及维持足够的脑灌注压。
近年来，脑组织氧分压（PbtO2）监测已成为一种临床有用的方式，是颅内压监测的一种补充。本文综述了PbtO2监测的生理学及其实际应用方面。
