Kleintierklinik Dr. S. Wisniewski, An der Rennbahn 16a, 76473 Iffezheim, Germany.
Parasitol Res. 2010 Feb;106(3):715-7. doi: 10.1007/s00436-009-1678-4.
This report describes the first assumed locally transmitted case of the eye worm Thelazia callipaeda in a dog living in southern Germany. A 4-year-old male golden retriever from the town of Bühl in north eastern Baden-Württemberg, about 10 km from the German-French border, showed one sided lacrimation for over 2 weeks. Despite the application of antibiotics, there was no improvement, and the dog additionally showed blepharospasmus, epiphora and red conjunctivas. A deepened eye inspection revealed five whitish filiform parasites that were morphologically identified as T. callipaeda. The partial sequence of the mitochondrial cytochrome c oxidase subunit 1 gene (cox1, 605 bp) from one specimen revealed a novel haplotype, which differs by 1.3% from the only one (haplotype 1) identified in Europe so far. Since the infected dog had never been abroad with the exception of two daytrips to the close Alsace region in France, the transmission of T. callipaeda most probably was domestic. With the presence of end hosts and Phortica flies nourishing on lachrymal secretions acting as intermediate hosts and an increasing number of dogs travelling to and coming from endemic regions in the South, the establishment of T. callipaeda in large parts of Europe cannot be excluded.
本报告描述了在德国南部一只犬身上首次发现眼虫 Thelazia callipaeda 的疑似本地传播病例。一只来自巴登-符腾堡州东北部比勒镇（距离德法边境约 10 公里）的 4 岁雄性金毛猎犬，单侧流泪超过 2 周。尽管使用了抗生素，病情仍未见改善，并且狗还出现了眼睑痉挛、溢泪和红色结膜。深入的眼部检查发现了五条白色线状寄生虫，经形态学鉴定为 T. callipaeda。从一个标本中提取的线粒体细胞色素 c 氧化酶亚基 1 基因（cox1，605bp）的部分序列揭示了一种新的单倍型，与迄今为止在欧洲发现的唯一一种（单倍型 1）相比差异为 1.3%。由于受感染的狗除了两次前往法国附近的阿尔萨斯地区一日游外从未出过国，因此 T. callipaeda 的传播极有可能是在国内发生的。随着终宿主和以泪液为食的 Phortica 蝇作为中间宿主的存在，以及越来越多的狗前往和来自南方的流行地区，T. callipaeda 在欧洲大部分地区的建立不能被排除。
