Infertility Center, Department of Surgery, Tor Vergata University Hospital, Rome, Italy.
Fertil Steril. 2010 Jul;94(2):755-7. doi: 10.1016/j.fertnstert.2009.10.014. Epub 2009 Nov 25.
Many studies evaluating a possible relationship between inherited thrombophilia and the etiology of unexplained infertility have been performed recently. No significant difference in the prevalence of three genetic mutations associated with the increased risk of thrombophilia (Factor V Leiden G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase [MTHFR] C677 T) was found in 100 infertile women with unexplained infertility when compared with 200 control fertile women without an infertility history.
最近进行了许多研究，评估遗传性血栓形成倾向与不明原因不孕的病因之间可能存在的关系。在 100 名患有不明原因不孕的不孕妇女与 200 名无不孕史的对照生育妇女中，未发现与血栓形成倾向风险增加相关的三种基因突变（因子 V 莱顿 G1691A、凝血酶原 G20210A 和亚甲基四氢叶酸还原酶 [MTHFR] C677T）的患病率存在显著差异。
