心脏浦肯野细胞。
Cardiac Purkinje cells.
机构信息
Department of Pharmacology, Columbia University, New York, NY, USA.
出版信息
Heart Rhythm. 2010 Jan;7(1):127-35. doi: 10.1016/j.hrthm.2009.09.017. Epub 2009 Sep 16.
PMID:19939742
Abstract
Purkinje cells are specialized for rapid propagation in the heart. Furthermore, Purkinje fibers as the source as well as the perpetuator of arrhythmias is a familiar finding. This is not surprising considering their location in the heart and their unique cell ultrastructure, cell electrophysiology, and mode of excitation-contraction coupling. This review touches on each of these points as we outline what is known today about Purkinje fibers/cells.
摘要
浦肯野细胞在心脏中具有快速传播的特性。此外，浦肯野纤维作为心律失常的起源和维持者是一种常见的发现。考虑到它们在心脏中的位置以及它们独特的细胞超微结构、细胞电生理学和兴奋-收缩耦联方式，这并不奇怪。在概述目前对浦肯野纤维/细胞的了解时，本文将涉及到这些要点。
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