Division of General Internal Medicine, Harborview Medical Center, Seattle, WA 98104, USA.
Postgrad Med. 2009 Nov;121(6):166-9. doi: 10.3810/pgm.2009.11.2085.
Celiac disease (CD) is an autoimmune disorder that causes varying degrees of villous atrophy and chronic malabsorption in genetically predisposed persons. Once considered a rare disease affecting children, younger adults, and persons of European ancestry, CD is increasingly recognized in all demographic groups with a prevalence rate in the United States of almost 1%. We offer an overview of the evaluation and management of CD vis-à-vis the case of a 41-year-old man who was hospitalized after presenting with the classic symptoms of chronic abdominal complaints, diarrhea, iron-deficiency anemia, and weight loss. Celiac disease remains an underdiagnosed condition in the United States, which is unfortunate given the potential treatment with a gluten-free diet.
乳糜泻（CD）是一种自身免疫性疾病，可导致遗传易感性个体出现不同程度的绒毛萎缩和慢性吸收不良。乳糜泻曾被认为是一种罕见疾病，主要影响儿童、年轻成年人和欧洲血统人群，但目前在美国所有人群中都有较高的患病率，几乎达到 1%。我们通过一个 41 岁男性患者的病例，概述了 CD 的评估和管理，该患者因慢性腹部不适、腹泻、缺铁性贫血和体重减轻等典型症状住院。在美国，乳糜泻仍然是一种未被充分诊断的疾病，这很遗憾，因为通过无麸质饮食可以进行有效的治疗。
