Zwolińska-Wcisło Małgorzata, Galicka-Latała Danuta, Sosin-Rudnicka Lucyna, Mach Tomasz, Rozpondek Piotr
Klinika Gastroenterologii i Hepatologii, Uniwersytet Jagielloński Collegium Medicum, Kraków.
Przegl Lek. 2009;66(8):466-8.
Celiac disease (gluten enteropathy) is chronic immunomediated disorder of gastrointestinal tract in genetically predisposed patients. We present the case of 46 years old man, with already diagnosed several autoimmune disorders, such as: diabetes mellitus LADA type, Graves-Basedow disease and vitiligo. Despite treatment of the above diseases, diarrhea and persistent abdominal pain was observed. Diagnosis of gluten enteropathy based on serology and histological evaluation of biopsies from distal part of duodenum enabled us to introduce gluten free diet, which contributed to attenuation of symptoms and better control of glucose serum levels. We think, that celiac disease should be taken into the consideration in differential diagnosis of chronic diarrhea and persistent abdominal pain, especially in patients with coexisting autoimmune diseases.
乳糜泻(麸质肠病)是一种发生于遗传易感性患者的慢性免疫介导性胃肠道疾病。我们报告了一名46岁男性的病例,他已被诊断患有多种自身免疫性疾病,如:成人隐匿性自身免疫性糖尿病、格雷夫斯-巴塞多氏病和白癜风。尽管对上述疾病进行了治疗,但仍观察到腹泻和持续性腹痛。基于血清学和十二指肠远端活检组织学评估诊断为麸质肠病,这使我们能够采用无麸质饮食,从而减轻了症状并更好地控制了血糖水平。我们认为,在慢性腹泻和持续性腹痛的鉴别诊断中,尤其是在患有自身免疫性疾病的患者中,应考虑乳糜泻。