• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

降钙素原:评估社区获得性肺炎严重程度的炎症生物标志物——老年患者的临床观察。

Procalcitonin: inflammatory biomarker for assessing the severity of community-acquired pneumonia--a clinical observation in geriatric patients.

机构信息

Klinikum Nürnberg, Medizinische Klinik 2-Akutgeriatrie, Lehrstuhl Innere Medizin-Geriatrie der FAU Erlangen-Nürnberg, Deutschland.

出版信息

Gerontology. 2010;56(4):385-9. doi: 10.1159/000262285. Epub 2009 Nov 25.

DOI:10.1159/000262285
PMID:19940454
Abstract

Community-acquired pneumonia is a common disease of the elderly and involves a high mortality risk. Demographic developments are creating new challenges for acute medical treatment strategies in geriatric patients with their underlying multimorbidity. In addition to the diagnostic parameters recorded on hospital admission, such as white cell count and C-reactive protein, procalcitonin, more than the risk scores CRB- and CURB-65 evaluated to date, appears to be a promising parameter for assessing the severity of pneumonia in elderly patients to allow early detection of severe courses and initiation of suitable treatment. The decisive factor is the dynamic course of the procalcitonin values over 3 consecutive days, as demonstrated in this case series.

摘要

社区获得性肺炎是老年人的常见病,死亡率高。人口结构的发展给患有多种基础疾病的老年患者的急性医疗治疗策略带来了新的挑战。除了入院时记录的白细胞计数和 C 反应蛋白等诊断参数外,降钙素原似乎比迄今为止评估的 CRB-和 CURB-65 风险评分更有希望作为评估老年患者肺炎严重程度的参数,以早期发现严重病程并开始适当的治疗。决定性因素是降钙素原值在连续 3 天内的动态变化,本病例系列研究证明了这一点。

相似文献

1
Procalcitonin: inflammatory biomarker for assessing the severity of community-acquired pneumonia--a clinical observation in geriatric patients.降钙素原:评估社区获得性肺炎严重程度的炎症生物标志物——老年患者的临床观察。
Gerontology. 2010;56(4):385-9. doi: 10.1159/000262285. Epub 2009 Nov 25.
2
Predictive values of semi-quantitative procalcitonin test and common biomarkers for the clinical outcomes of community-acquired pneumonia.半定量降钙素原检测及常见生物标志物对社区获得性肺炎临床结局的预测价值。
Respir Care. 2014 Apr;59(4):564-73. doi: 10.4187/respcare.02807. Epub 2013 Oct 29.
3
Utility of procalcitonin, C-reactive protein and white blood cells alone and in combination for the prediction of clinical outcomes in community-acquired pneumonia.降钙素原、C反应蛋白及白细胞单独及联合应用对社区获得性肺炎临床结局的预测价值
Clin Chem Lab Med. 2015 Mar;53(4):559-66. doi: 10.1515/cclm-2014-0456.
4
C-reactive protein, procalcitonin, clinical pulmonary infection score, and pneumonia severity scores in nursing home acquired pneumonia.养老院获得性肺炎中的C反应蛋白、降钙素原、临床肺部感染评分及肺炎严重程度评分
Respir Care. 2014 Apr;59(4):574-81. doi: 10.4187/respcare.02741. Epub 2013 Oct 8.
5
Inflammatory biomarkers and prediction for intensive care unit admission in severe community-acquired pneumonia.炎症生物标志物与重症社区获得性肺炎患者入住重症监护病房的预测。
Crit Care Med. 2011 Oct;39(10):2211-7. doi: 10.1097/CCM.0b013e3182257445.
6
Procalcitonin predicts patients at low risk of death from community-acquired pneumonia across all CRB-65 classes.降钙素原可预测所有CRB-65分级中社区获得性肺炎死亡低风险患者。
Eur Respir J. 2008 Feb;31(2):349-55. doi: 10.1183/09031936.00054507. Epub 2007 Oct 24.
7
The value of procalcitonin level in community-acquired pneumonia in the ED.降钙素原水平在急诊科社区获得性肺炎中的价值。
Am J Emerg Med. 2012 Sep;30(7):1248-54. doi: 10.1016/j.ajem.2011.08.009. Epub 2011 Oct 24.
8
Biomarkers in community-acquired pneumonia.社区获得性肺炎的生物标志物。
Expert Rev Respir Med. 2012 Apr;6(2):203-14. doi: 10.1586/ers.12.6.
9
Performance of pro-adrenomedullin for identifying adverse outcomes in community-acquired pneumonia.降肾上腺髓质素原对社区获得性肺炎不良结局的识别性能。
J Infect. 2015 May;70(5):457-66. doi: 10.1016/j.jinf.2014.12.003. Epub 2014 Dec 11.
10
Procalcitonin levels are lower in intensive care unit patients with H1N1 influenza A virus pneumonia than in those with community-acquired bacterial pneumonia. A pilot study.降钙素原水平在 H1N1 流感 A 病毒肺炎的重症监护病房患者中低于社区获得性细菌性肺炎的患者。一项初步研究。
J Crit Care. 2011 Apr;26(2):201-5. doi: 10.1016/j.jcrc.2010.07.009. Epub 2010 Sep 1.

引用本文的文献

1
Reduced Prognostic Role of Serum PCT Measurement in Very Frail Older Adults Admitted to the Emergency Department.血清降钙素原检测在急诊收治的极度虚弱老年人中的预后价值降低。
Antibiotics (Basel). 2023 Jun 10;12(6):1036. doi: 10.3390/antibiotics12061036.
2
Intensive care of geriatric patients-a thin line between under- and overtreatment.老年患者的重症监护——过度治疗与治疗不足之间的微妙平衡。
Wien Med Wochenschr. 2022 Apr;172(5-6):102-108. doi: 10.1007/s10354-021-00902-1. Epub 2022 Jan 10.
3
The Clinical Significance of Procalcitonin Elevation in Patients over 75 Years Old Admitted for COVID-19 Pneumonia.
75 岁以上因 COVID-19 肺炎住院患者降钙素原升高的临床意义。
Mediators Inflamm. 2021 Jun 28;2021:5593806. doi: 10.1155/2021/5593806. eCollection 2021.
4
Outpatient Antibiotic Prescription.门诊抗生素处方
Dtsch Arztebl Int. 2016 Jul 1;113(26):454-9. doi: 10.3238/arztebl.2016.0454.
5
C-reactive protein and the acute phase reaction in geriatric patients.老年患者的C反应蛋白与急性期反应
Z Gerontol Geriatr. 2015 Oct;48(7):595-600. doi: 10.1007/s00391-015-0938-4. Epub 2015 Sep 3.
6
[Recognition of infections in elderly emergency patients].[老年急诊患者感染的识别]
Z Gerontol Geriatr. 2015 Oct;48(7):601-7. doi: 10.1007/s00391-015-0903-2. Epub 2015 May 19.