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2009年佛罗里达州消防员锑中毒的假性暴发

Pseudo-outbreak of antimony toxicity in firefighters - Florida, 2009.

出版信息

MMWR Morb Mortal Wkly Rep. 2009 Nov 27;58(46):1300-2.

Abstract

Antimony oxides, in combination with halogens, have been used as flame retardants in textiles since the 1960s. Uniforms made from fabric containing antimony are common among the estimated 1.1 million firefighters in the United States. In October 2008, CDC received a report from the fire chief of a fire department in Florida (fire department A) regarding an outbreak of antimony toxicity among 30 firefighters who had elevated antimony levels detected in hair samples. This report summarizes the ensuing health hazard evaluation conducted by CDC to determine the source of antimony exposure. In February 2009, CDC administered questionnaires to and collected urine samples from two groups of firefighters: 20 firefighters from fire department A who did not wear pants made from antimony-containing fabric, and 42 firefighters from fire department B (also located in Florida) who did. All 20 firefighters from fire department A and 41 (98%) from fire department B had urine antimony concentrations below or within the laboratory reference range. CDC concluded that wearing pants made from antimony-containing fabric was not associated with elevated levels of urinary antimony. Only validated methods (e.g., urine testing) should be used for the determination of antimony toxicity. Accurate and timely risk communication during suspected workplace exposures should underscore the importance of using validated tests, thereby refuting an unproven hypothesis, allaying unsubstantiated concerns, and enhancing public trust.

摘要

自20世纪60年代以来,氧化锑与卤素结合,一直被用作纺织品的阻燃剂。在美国约110万名消防员中,由含锑织物制成的制服很常见。2008年10月,美国疾病控制与预防中心(CDC)收到佛罗里达州一个消防部门(消防部门A)消防队长的报告,称30名消防员出现锑中毒疫情,其头发样本中锑含量升高。本报告总结了CDC随后进行的健康危害评估,以确定锑暴露的来源。2009年2月,CDC向两组消防员发放问卷并采集尿液样本:一组是来自消防部门A的20名未穿着含锑织物裤子的消防员,另一组是来自消防部门B(也位于佛罗里达州)的42名穿着含锑织物裤子的消防员。消防部门A的所有20名消防员以及消防部门B的41名(98%)消防员尿液中的锑浓度均低于或在实验室参考范围内。CDC得出结论,穿着含锑织物裤子与尿液中锑水平升高无关。只有经过验证的方法(如尿液检测)应用于确定锑中毒情况。在疑似工作场所接触期间,准确及时的风险沟通应强调使用经过验证的检测方法的重要性,从而反驳未经证实的假设,消除无根据的担忧,并增强公众信任。

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