Siqueira Luciano de Oliveira, Muccini Tiane, Dall Agnol Iandra, Filla Lauren, Tibbola Paula, Luvison Andiara, Costa Leandro, Moreira José Cláudio Fonseca
Curso de Farmácia, Instituto de Ciências Biológicas, Universidade de Passo Fundo, Passo Fundo, RS, Brasil.
Arq Bras Endocrinol Metabol. 2009 Oct;53(7):844-52. doi: 10.1590/s0004-27302009000700008.
The aim of this study was to analyze biochemical markers as indicators of athletic performance, in light of a clinical context and athletic.
Samples of peripheral blood (8 mL) and urine (50 mL) were collected from 20 marathon athletes at rest and 15 minutes after half marathon. Following, examination of blood, urine and serum markers of renal function, muscle damage and lipidic profile was carried out.
Statistical analysis of the results showed a significant increase (p < 0.05) in serum activity of the enzymes CK, CK-MM, CK-MB and LDH, serum creatinine and iron, leukocyte count and neutrophils. Furthermore, triglycerides, VLDL, uric acid in serum showed a significant decrease.
This study shows that athletes of marathon show changes in biochemical parameters of blood and urine after competing in this modality, which demonstrates the importance of carrying out laboratory tests as diagnosis for silent biochemical disorders.
本研究旨在结合临床背景和运动情况，分析生化标志物作为运动表现指标的情况。
从20名马拉松运动员休息时及半程马拉松赛后15分钟采集外周血（8毫升）和尿液（50毫升）样本。随后，对血液、尿液和血清中的肾功能、肌肉损伤及脂质谱标志物进行检测。
结果的统计分析显示，酶CK、CK-MM、CK-MB和LDH的血清活性、血清肌酐、铁、白细胞计数和中性粒细胞显著增加（p < 0.05）。此外，血清中的甘油三酯、极低密度脂蛋白、尿酸显著降低。
本研究表明，马拉松运动员在参加此项运动后，血液和尿液的生化参数会发生变化，这证明了进行实验室检测以诊断隐匿性生化紊乱的重要性。
