Fellman Johan, Eriksson Aldur W
Folkhälsan Institute of Genetics, Department of Genetic Epidemiology, Helsinki, Finland.
Twin Res Hum Genet. 2009 Dec;12(6):583-90. doi: 10.1375/twin.12.6.583.
Strong geographical variations in the twinning rate have been presented in the literature. In general, the rate is high among people of African origin, intermediate among Europeans and low among most Asiatic populations. In Europe, a progressive increase has occurred in the twinning rate from south to north, with a minimum around the Basque provinces. The highest twinning rates in Europe have been found among Nordic populations with the exception of the Saamis (Lapps). Within larger populations, some small isolated subpopulations have been identified to have extreme, mainly high, twinning rates. In this study, we investigated the regional variation of the twinning rate in Sweden. We analysed twinning rates for different counties for the period 1751-1850. From the middle of the 19th century, the environmental and genetic differences have decreased and the regional twinning rates have converged towards a common decreased level. The models applied have the geographical coordinates as regressors. The optimal model for the twinning rate has the longitude, the latitude and their product as regressors, indicating both horizontal and vertical trends. According to this model, the maximum twinning rate in Sweden is located in the eastern part of central Sweden, mainly on the island of Gotland and in the counties around Stockholm. Relatively low twinning rates are seen in the western and northern parts of Sweden.
文献中已呈现出双胞胎出生率存在显著的地域差异。总体而言,非洲裔人群的双胞胎出生率较高,欧洲人群的出生率处于中等水平,而大多数亚洲人群的出生率较低。在欧洲,双胞胎出生率从南向北呈逐渐上升趋势,在巴斯克省附近降至最低。除萨米人(拉普人)外,北欧人群的双胞胎出生率在欧洲最高。在较大的人群中,已发现一些小型孤立亚群的双胞胎出生率极高,主要是高出生率。在本研究中,我们调查了瑞典双胞胎出生率的区域差异。我们分析了1751年至1850年期间不同郡县的双胞胎出生率。自19世纪中叶以来,环境和遗传差异减小,区域双胞胎出生率趋向于一个共同的降低水平。所应用的模型以地理坐标作为回归变量。双胞胎出生率的最优模型以经度、纬度及其乘积作为回归变量,表明了水平和垂直趋势。根据该模型,瑞典双胞胎出生率最高的地区位于瑞典中部的东部,主要在哥特兰岛以及斯德哥尔摩周边的郡县。瑞典西部和北部的双胞胎出生率相对较低。