Department of Cardiovascular Surgery, Tokushima Red Cross Hospital, 103 Irinoguchi, Komatsushima-cho, Komatsushima-shi, Tokushima 773-8502, Japan.
J Cardiol. 2009 Dec;54(3):466-9. doi: 10.1016/j.jjcc.2009.02.012. Epub 2009 Apr 1.
A 69-year-old woman with a history of graft replacement of descending aortic aneurysm was referred to our hospital due to massive hematemesis with shock status. Additionally, the deterioration of respiratory status made us start the management under mechanical ventilation. The emergent gastrointestinal endoscopy by a general practitioner showed ulcer-like lesion of the upper esophagus and arterial bleeding. A contrast-enhanced computed tomography showed thoracic aortic aneurysm surrounded by low density mass and contrast medium protruding from the aneurysm. The findings suggested that thoracic aortic aneurysm perforated into esophagus and made an aortoesophageal fistula. Hemodynamic deterioration rapidly progressed and she passed away 4 days after her hospitalization. Autopsy showed that a new thoracic aortic aneurysm arose from the proximal site of the graft. The aneurysm ruptured to esophagus with 6.0 cm x 5.0 cm sized fistula. The fistula was filled with a large thrombus. The large thrombus filling with the fistula worked as the tamponade and prevented her from the fatal exsanguinations and sudden death. The mechanism of the sentinel bleeding and the fatal exsanguinations known as Chiari's triad was revealed in our report.
一位 69 岁女性,有降主动脉瘤移植置换的病史,因大量呕血伴休克状态转入我院。此外,呼吸状况恶化,使我们开始在机械通气下进行治疗。普通内科医生进行的紧急胃肠内镜检查显示食管上段呈溃疡样病变和动脉出血。增强 CT 显示胸主动脉瘤周围有低密度肿块和对比剂从动脉瘤突出。这些发现提示胸主动脉瘤穿破食管形成主动脉-食管瘘。血流动力学迅速恶化,她在住院后 4 天去世。尸检显示新的胸主动脉瘤出现在移植物的近端部位。动脉瘤破裂至食管,形成 6.0cm x 5.0cm 大小的瘘口。瘘口充满了大血栓。充满瘘口的大血栓起到了填塞作用,防止了致命性出血和猝死。我们的报告揭示了 Chiari 三联征(即哨兵性出血和致命性出血的机制)。