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机器人根治性宫颈切除术治疗早期宫颈癌的安全性和可行性。

Safety and feasibility of robotic radical trachelectomy in patients with early-stage cervical cancer.

机构信息

Department of Gynecologic Oncology, Unit 440, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

出版信息

Gynecol Oncol. 2010 Mar;116(3):512-5. doi: 10.1016/j.ygyno.2009.10.063. Epub 2009 Nov 26.

Abstract

OBJECTIVE

This study aimed to determine the safety and feasibility of robotic radical trachelectomy and bilateral pelvic lymphadenectomy. We also describe our surgical technique.

METHODS

This is a retrospective review of all patients who underwent robotic radical trachelectomy and bilateral pelvic lymphadenectomy from October 2008 to May 2009. We analyzed our data to evaluate the safety and feasibility of this surgery.

RESULTS

This analysis included 4 patients with early-stage squamous cell carcinoma of the cervix. The median body mass index was 27.1 kg/m(2) (range, 22.7 to 39.1). Three patients had stage IA2 adenocarcinoma; 1 patient had stage IA1 adenocarcinoma with lymph-vascular space invasion. The median operative time was 339.5 min (range, 245 to 416). The median console time was 282.5 min (range, 217 to 338). The median estimated blood loss was 62.5 ml (range, 50 to 75). There were no conversions to laparotomy. There were no intraoperative complications. No patient required blood transfusion. The median length of hospital stay was 1.5 days (range, 1 to 2). One patient experienced a postoperative complication, transient left lower extremity sensory neuropathy. No patient had residual tumor in the trachelectomy specimen, and no patient underwent adjuvant therapy. The median number of pelvic lymph nodes removed was 20 (range, 18 to 27). The median time to a successful voiding trial was 8 days (range, 7 to 9). The median follow-up was 105 days (range, 82 to 217). There were no recurrences.

CONCLUSION

Robotic radical trachelectomy and bilateral pelvic lymphadenectomy is feasible and safe and should be considered for patients desiring fertility-sparing surgery.

摘要

目的

本研究旨在确定机器人根治性宫颈切除术和双侧盆腔淋巴结清扫术的安全性和可行性。我们还描述了我们的手术技术。

方法

这是一项对 2008 年 10 月至 2009 年 5 月期间所有接受机器人根治性宫颈切除术和双侧盆腔淋巴结清扫术的患者进行的回顾性分析。我们分析了我们的数据,以评估该手术的安全性和可行性。

结果

本分析包括 4 例早期宫颈鳞癌患者。中位体质指数为 27.1kg/m2(范围 22.7 至 39.1)。3 例为 IA2 期腺癌;1 例为 IA1 期腺癌伴淋巴管血管间隙浸润。中位手术时间为 339.5 分钟(范围 245 至 416)。中位控制台时间为 282.5 分钟(范围 217 至 338)。中位估计出血量为 62.5ml(范围 50 至 75)。无中转开腹。无术中并发症。无患者需要输血。中位住院时间为 1.5 天(范围 1 至 2)。1 例患者出现术后并发症,短暂左侧下肢感觉神经病。宫颈切除标本中无残留肿瘤,无患者接受辅助治疗。中位盆腔淋巴结清扫数为 20 枚(范围 18 至 27)。成功排尿试验的中位时间为 8 天(范围 7 至 9)。中位随访时间为 105 天(范围 82 至 217)。无复发。

结论

机器人根治性宫颈切除术和双侧盆腔淋巴结清扫术是可行和安全的,对于希望保留生育能力的患者应考虑采用该手术。

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