Department of Plant Systems Biology, Ghent University, 9052 Ghent, Belgium.
Eur J Cell Biol. 2010 Feb-Mar;89(2-3):231-5. doi: 10.1016/j.ejcb.2009.11.003. Epub 2009 Nov 26.
The directional transport of the plant hormone auxin is a unique process mediating a wide variety of developmental processes. Auxin movement between cells depends on AUX1/LAX, PGP and PIN protein families that mediate auxin transport across the plasma membrane. The directionality of auxin flow within tissues is largely determined by polar, subcellular localization of PIN auxin efflux carriers. PIN proteins undergo rapid subcellular dynamics that is important for the process of auxin transport and its directionality. Furthermore, various environmental and endogenous signals can modulate trafficking and polarity of PIN proteins and by this mechanism change auxin distribution. Thus, the subcellular dynamics of auxin transport proteins represents an important interface between cellular processes and development of the whole plant. This review summarizes our recent contributions to the field of PIN trafficking and auxin transport regulation.
植物激素生长素的定向运输是一种独特的过程，介导着各种各样的发育过程。细胞间生长素的移动依赖于 AUX1/LAX、PGP 和 PIN 蛋白家族，它们介导着质膜间生长素的运输。组织内生长素流动的方向性在很大程度上取决于 PIN 生长素外排载体的极性、亚细胞定位。PIN 蛋白经历快速的亚细胞动力学，这对于生长素运输及其方向性的过程很重要。此外，各种环境和内源性信号可以调节 PIN 蛋白的运输和极性，通过这种机制改变生长素的分布。因此，生长素运输蛋白的亚细胞动力学代表了细胞过程和整个植物发育之间的一个重要界面。本综述总结了我们在 PIN 运输和生长素运输调控领域的最新贡献。
